2022
DOI: 10.2139/ssrn.4163670
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Microbial Diversity and Potential Biodegradation Risk Assessment of Archaeological Ruins of Liangzhu City

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“…Among different kinds of inflammatory cells, macrophages are particularly interesting, as they are highly heterogeneous cell populations with distinct phenotypes and functions [10,11]. In response to kidney injury, macrophages are activated and polarized in a dynamic fashion, and display a spectrum of phenotypes ranging from pro-inflammatory (M1) to anti-inflammatory (M2) [12,13]. Although it is well documented that renal infiltration of macrophages is closely associated with the severity of kidney fibrosis [13,14], exactly how macrophages contribute to fibroblast activation and expansion in the fibrotic kidney remains poorly understood.…”
Section: Ivyspringmentioning
confidence: 99%
“…Among different kinds of inflammatory cells, macrophages are particularly interesting, as they are highly heterogeneous cell populations with distinct phenotypes and functions [10,11]. In response to kidney injury, macrophages are activated and polarized in a dynamic fashion, and display a spectrum of phenotypes ranging from pro-inflammatory (M1) to anti-inflammatory (M2) [12,13]. Although it is well documented that renal infiltration of macrophages is closely associated with the severity of kidney fibrosis [13,14], exactly how macrophages contribute to fibroblast activation and expansion in the fibrotic kidney remains poorly understood.…”
Section: Ivyspringmentioning
confidence: 99%