Microbial degradation of steroidal estrogens

Yu, Chang‐Ping; Deeb, Rula A.; Chu, Kung-Hui

doi:10.1016/j.chemosphere.2013.01.112

Cited by 169 publications

(101 citation statements)

References 92 publications

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“…2). It is known that E2 is metabolized to E1 and E3 by organisms (Yu et al 2013). These metabolites are also estrogenic, although less potent than parent E2 (Caldwell et al 2012).…”

Section: Resultsmentioning

confidence: 99%

“…Thus, in vivo degradation was presumed to be the principal mechanism of E2 transformation. E1 and E3 were generated as the intermediate metabolites as the scenario in typical biological degradation systems (Yu et al 2013). Figure 4 illustrates the change of total estrogen (E1 ?…”

Section: Resultsmentioning

confidence: 99%

“…Enzymes capable of degrading E2 show similar effects on other steroidal hormones, such as E1, E3 and EE2 (Yu et al 2013). Phanerochaete chrysosporium is the most intensively studied strain of white rot fungi that produces extracellular enzymes responsible for the degradation of pollutants (Bumpus et al 1985;Glenn and Gold 1985;Vazquez-Duhalt et al 1994).…”

mentioning

confidence: 99%

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Transformation of 17β-Estradiol by Phanerochaete chrysosporium in Different Culture Media

Zhou

Luo²,

et al. 2015

Bull Environ Contam Toxicol

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The removal of 17β-estradiol (E2) by white-rot fungus Phanerochaete chrysosporium cultured in classic Kirk or potato medium was systematically investigated. Results demonstrated that E2 can be efficiently removed regardless of culture media type. However, the reaction intermediates and transformation pathways varied in different media. Estrone (E1) and estriol (E3) were sequentially generated as intermediates in the potato medium, but these intermediates were absent in Kirk medium. Such results were found to correlate to the peroxidases produced in Kirk medium. These enzymes catalyzed one-electron oxidation of E2 to form radicals that can undergo oxidative coupling. Similar enzymes were not detected in the potato medium, thus E2 underwent in vitro oxidation to form E1 and E3 sequentially. Adding glucose to the potato medium further accelerated such processes. The findings in this study provide insights into estrogen reactions mediated by P. chrysosporium and for potential development of biodegradation methods to reduce estrogen contamination levels.

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“…2). It is known that E2 is metabolized to E1 and E3 by organisms (Yu et al 2013). These metabolites are also estrogenic, although less potent than parent E2 (Caldwell et al 2012).…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Transformation of 17β-Estradiol by Phanerochaete chrysosporium in Different Culture Media

Zhou

Luo²,

et al. 2015

Bull Environ Contam Toxicol

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“…Steroidal estrogens, naturally (estrone, E1; 17b-estradiol, E2; estriol, E3) or synthetically (17a-ethinylestradiol, EE2) produced, are considered as one of the major category of endocrine disrupting compounds and cause increasing concern for its sexual disruption on male fish in natural water bodies even at the concentration of nanogram per liter (Jobling et al, 1998;Yu et al, 2013). The occurrence of steroidal estrogens in the natural water environment is a consequence of discharge from wastewater treatment plants (WWTPs) due to incompletely removal of these contaminants by traditional wastewater treatment processes (Andersen et al, 2003;Benotti et al, 2008;Johnson and Sumpter, 2001;Kolpin et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

Removal of environmental estrogens by bacterial cell immobilization technique

Qin

Sun

et al. 2016

Chemosphere

Self Cite

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“…This process is observed when bacteria use their existing enzymes to degrade steroidal hormones (Hamid and Eskicioglu, 2012;Yu et al, 2013). However, the positive effect of methanol was the same in the three studied cases because its concentration was held constant (750 mg L -1 ), which was done to compare the effects of the three different media.…”

Section: Medium: Synthetic Wastewater Water and The Supernatant Solumentioning

confidence: 99%

Removal of Estrogens by Activated Sludge Under Different Conditions Using Batch Experiments

Bernardelli

Liz

Belli

et al. 2015

Braz. J. Chem. Eng.

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-Wastewater treatment by deactivated and activated sludge was investigated to evaluate the removal of estrogens [estrone (E1), 17β-estradiol (E2), 17α-ethinylestradiol (EE2)] via adsorption and degradation. Different treatment conditions were used, including three mixed liquor volatile suspended solid (MLVSS) concentrations, three methanol concentrations (carbon source) and three types of aqueous media (water, synthetic solution, and supernatant). The E2 was degraded the fastest by the bacterial community. In all cases the removal rate increased when the initial MLVSS and methanol concentrations increased and when the macro-and micronutrients were present in the solution. In the experiments with deactivated sludge, the synthetic compound EE2 was more easily removed via sorption. The bacterial communities of the activated sludge were studied, which indicated a similarity of more than 75% between the different samples. A similarity of only 50% was found between the activated and deactivated sludges.

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Microbial degradation of steroidal estrogens

Cited by 169 publications

References 92 publications

Transformation of 17β-Estradiol by Phanerochaete chrysosporium in Different Culture Media

Transformation of 17β-Estradiol by Phanerochaete chrysosporium in Different Culture Media

Removal of environmental estrogens by bacterial cell immobilization technique

Removal of Estrogens by Activated Sludge Under Different Conditions Using Batch Experiments

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