Microbial degradation of polyurethane

New insights into the microbial degradation of polyurethanes

“…75 Puried PUases presented either protease or esterase activity and would be blocked by serine hydrolase inhibitor, soybean trypsin inhibitor, or bivalent cation chelator. Recombinant esterases, proteases, and ureases could digest PU through cleaving the ester or peptide bonds.…”

“…Recombinant esterases, proteases, and ureases could digest PU through cleaving the ester or peptide bonds. 75 Puried PUases presented either protease or esterase activity and would be blocked by serine hydrolase inhibitor, soybean trypsin inhibitor, or bivalent cation chelator. Therefore, the putative PUases did not restrict to a single type of enzyme.…”

Glutathione-responsive biodegradable poly(urea-urethane)s containing L-cystine-based chain extender

“…In a wide variety of applications as biomaterials, PU was especially utilized in implantable devices such as drug administration carriers [3,4], artificial blood vessels [5,6], heart valves [7][8][9], nucleus prosthesis [10,11], and other tissue engineering materials [12,13]. Some articles have reported biodegradable PU or poly(urea-urethane)s, mainly depending on the soft segment undergoing hydrolytic, enzymatic, and oxidative pathways [14][15][16][17][18], in which hydrolyzation of polyester and oxidation of polyether were the most common pattern [19][20][21]. However, despite the decomposition of ester and ether groups often autocatalytically accelerated, the degradation of these polymers still covered a long process and hard to control.…”

Nanoparticles Production and Inclusion in <i>S. aureus</i> Incubated with Polyurethane: An Electron Microscopy Analysis

“…In fact prostheses in the oral cavity are constantly attacked by microorganisms and their colonization often concurs in the destruction of the artificial materials. This can lead to the release of allergenic substances, toxic to the human body [2,[4][5][6].…”