Microbial community compositional analysis for membrane bioreactor treating antibiotics containing wastewater

Zhu, Yijing; Wang, Yayi; Jiang, Xuxin; Zhou, Shuai; Wu, Min; Pan, Mianli; Chen, Hao

doi:10.1016/j.cej.2017.05.073

Cited by 141 publications

(32 citation statements)

References 51 publications

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“…Sulfonamides were reported to be mainly removed by biodegradation and tetracyclines by adsorption [18,41]. The negligible adsorption of sulfonamides to sludge may be associated with its high solubility in water; in contrast, the significant rapid adsorption of tetracycline onto activated sludge is due to its molecular form and complexation [43].…”

Section: Resultsmentioning

confidence: 99%

Evolution of Antibiotic Resistance and the Relationship between the Antibiotic Resistance Genes and Microbial Compositions under Long-Term Exposure to Tetracycline and Sulfamethoxazole

Yang

Ruifei

et al. 2019

IJERPH

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The removal of antibiotics and widespread of antibiotic resistance genes (ARGs) have received continuous attention due to the possible threats to environment. However, little information is available on the evolution of antibiotic resistance and the relationship between ARGs and microbial communities under long-term exposure to sub-inhibitory concentrations of antibiotics. In our study, two laboratory-scale anoxic-aerobic wastewater treatment systems were established and operated for 420 days to investigate the evolution of antibiotic resistance under exposure of 5 mg·L−1 tetracycline (TC) or 5 mg·L−1 TC and 1 mg·L−1 sulfamethoxazole (SMX). The average removal rates of TC and SMX were about 59% and 72%, respectively. The abundance of the main ARGs responsible for resistance to TC and SMX increased obviously after antibiotics addition, especially when TC and SMX in combination (increased 3.20-fold). The tetC and sul1 genes were the predominant genes in the development of TC and SMX resistance, in which gene sul1 had the highest abundance among all the detected ARGs. Network analysis revealed that under antibiotic pressure, the core bacterial groups carrying multiple ARGs formed and concentrated in about 20 genera such as Dechloromonas, Candidatus Accumulibacter, Aeromonas, Rubrivivax, in which intI1 played important roles in transferring various ARGs except sul3.

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Section: Resultsmentioning

confidence: 99%

Evolution of Antibiotic Resistance and the Relationship between the Antibiotic Resistance Genes and Microbial Compositions under Long-Term Exposure to Tetracycline and Sulfamethoxazole

Yang

Ruifei

et al. 2019

IJERPH

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“…Other data help in elucidating the fact that denitrification processes are more vulnerable than nitrification and carbon oxidization processes under SMX stress. Indeed, the relative abundance of denitrifiers decreased by 86% at a SMX concentration of 2000 mg L À1 (Zhu et al, 2017).…”

Section: Impact Of Phacs In the Microbial Communities Of Wwt Systemsmentioning

confidence: 99%

Environmental impact and biological removal processes of pharmaceutically active compounds: The particular case of sulfonamides, anticonvulsants and steroid estrogens

Leal

Mesquita

Amaral

et al. 2019

Critical Reviews in Environmental Science and Technology

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Pharmaceutically active compounds (PhACs) have recently received wide attention in the scientific community due to their extensive consumption for human health and consequent discharge to the environment. Release of PhACs into the environment, even in trace amounts, can cause serious environmental damage. This has become a major concern and their removal from water sources is a priority. Although a few PhACs are efficiently removed in wastewater treatment plants (WWTPs), others remain recalcitrant, and their release is causing damage. In this review, the current state of the art on the biological removal processes of sulfonamide sulfamethoxazole (SMX), the anticonvulsant carbamazepine (CBZ), and steroid estrogens 17b-estradiol (E2) and 17a-ethinylestradiol (EE2) are discussed, along with their environmental impact. Other systems beyond activated sludge, such as membrane bioreactors, enzymatic membrane reactors, fungi treatments and hybrid systems are also becoming of major interest and are being evaluated for the removal of these compounds. Future perspectives are addressed.

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“…[2][3][4][5] The treatment of antibiotic wastewater has become a signicant problem in the eld of sewage treatment. A large body of research has explored the factors that affect the biological treatment of antibiotic wastewater, i.e., sludge age, reaction time and temperature, 6 microbial community, 7 and different co-metabolism substrates. 8 These studies have explored the mechanism of biodegradation of antibiotics from a macro perspective.…”

Section: Introductionmentioning

confidence: 99%

Identification of ceftazidime interaction with bacteria in wastewater treatment by Raman spectroscopic mapping

Peng

Wei

et al. 2019

RSC Adv.

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Raman spectroscopy yields a fingerprint spectrum and is of great importance in medical and biological sciences as it is non-destructive, non-invasive, and available in the aqueous environment. In this study, Raman spectroscopy and Raman mapping were used to explore the dynamic biochemical processes in screened bacteria under ceftazidime stress. The Raman spectral difference between bacteria with and without antibiotic stress was analyzed by principal component analysis and characteristic peaks were obtained. The results showed that amino acids changed first and lipids were reduced when bacteria were exposed to ceftazidime stress. Furthermore, in Raman mapping, when bacteria were subjected to antibiotic stress, the peak at 1002 cm À1 (phenylalanine) increased, while the peak at 1172 cm À1 (lipids)weakened. This indicates that when bacteria were stimulated by antibiotics, the intracellular lipids decreased and the content of specific amino acids increased. The reduction of intracellular lipids may suggest a change of membrane permeability. The increase of specific amino acids suggests that bacteria resist external stimuli of antibiotics by regulating the activities of related enzymes. This study explored the processes of the action between bacteria and antibiotics by Raman spectroscopy, and provides a foundation for the further study of the dynamics of microbial biochemical processes in the future. Fig. 8 Raman mappings of bacteria in ceftazidime solution with tolerance times of 0 min (a), 30 min (b), 60 min (c), 90 min (d), and 120 min (e).

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Microbial community compositional analysis for membrane bioreactor treating antibiotics containing wastewater

Cited by 141 publications

References 51 publications

Evolution of Antibiotic Resistance and the Relationship between the Antibiotic Resistance Genes and Microbial Compositions under Long-Term Exposure to Tetracycline and Sulfamethoxazole

Evolution of Antibiotic Resistance and the Relationship between the Antibiotic Resistance Genes and Microbial Compositions under Long-Term Exposure to Tetracycline and Sulfamethoxazole

Environmental impact and biological removal processes of pharmaceutically active compounds: The particular case of sulfonamides, anticonvulsants and steroid estrogens

Identification of ceftazidime interaction with bacteria in wastewater treatment by Raman spectroscopic mapping

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