Microbial colonization of Provox voice prosthesis in the Indian scenario

Chaturvedi, Pankaj; Syed, Salam A.; Pawar, PV; Kelkar, Rohini; Biswas, Sanjay; Datta, S; Nair, Deepa; Chaukar, Devendra A; D'Cruz, A.K.

doi:10.4103/0019-509x.138303

Cited by 5 publications

(3 citation statements)

References 15 publications

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“…There is a variety of data published about VP lifespan. Some authors assessed that the average time of Provox Vega exploitation ranges from 3.5–18 months [ 27 , 28 ]. The average and median number of replacements per year is smaller than in another study, where the results were an average of 2.2 replacements and a median of 4.1 replacements per year [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

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Biofilm Growth Causes Damage to Silicone Voice Prostheses in Patients after Surgical Treatment of Locally Advanced Laryngeal Cancer

et al. 2020

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Voice prosthesis implantation with the creation of a tracheoesophageal fistula is the gold standard procedure for voice rehabilitation in patients after a total laryngectomy. All patients implanted with a voice prosthesis (VP) have biofilms of fungi and bacteria grow on their surface. Biofilm colonization is one of the main reasons for VP degradation that can lead to VP dysfunction, which increases the high risk of pneumonia. In a 20-month evaluation period, 129 cases of prostheses after replacement procedures were investigated. Microbiological examination of the biofilms revealed that there were four of the most common fungi species (Candida spp.) and a large variety of bacterial species present. We studied the relationship between the time of proper function of Provox VP, the microorganism composition of the biofilm present on it, and the degradation level of the silicone material. Evaluation of the surface of the removed VP using an atomic force microscope (AFM) has demonstrated that biofilm growth might drastically change the silicone’s mechanical properties. Changes in silicone stiffness and thermal properties might contribute to the failure of VP function. Our data can serve in future studies for the development of methods to prevent or inhibit biofilm formation on the VP surface that would translate to an increase in their durability and safety.

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Section: Discussionmentioning

confidence: 99%

“…Factors influencing the time of voice prosthesis degradation are primary or postoperative irradiation for the head and neck region, as well as diet. Some studies have proven that consuming large quantities of dairy products has a significant effect on the extension of VP exploitation time [ 28 ].…”

Section: Introductionmentioning

confidence: 99%

Biofilm Growth Causes Damage to Silicone Voice Prostheses in Patients after Surgical Treatment of Locally Advanced Laryngeal Cancer

et al. 2020

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“…It is however likely that differences in the identification methods used, different patient demographics or lifestyles and different lifestyles or dietary habits will impact upon the microbial colonization of VP. For instance, Chaturvedi et al (2014) found that C. tropicalis was the most prevalent fungal species colonizing VP within an Indian patient cohort. The high consumption of dairy products such as yogurt and buttermilk in India has been proposed to influence biofilm growth on VPs.…”

Section: Discussionmentioning

confidence: 99%

Precision Antifungal Treatment Significantly Extends Voice Prosthesis Lifespan in Patients Following Total Laryngectomy

et al. 2020

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Analysis of Factors Affecting the Longevity of Voice Prosthesis Following Total Laryngectomy with a Review of Literature

Khwajamohiuddin

2017

Indian J Surg Oncol

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Tracheoesophageal voice puncture (TEP) coupled with the use of voice prosthesis has been considered as the gold standard for speech rehabilitation in patients of advanced laryngeal/hypopharyngeal carcinomas, who have undergone a total laryngectomy with or without partial pharyngectomy. Although prosthetic voice rehabilitation is commonly practiced worldwide including India, there is a paucity of published Indian data, more so in the current era of organ conservation. This study included 60 laryngectomized patients with a prosthetic voice rehabilitation at a tertiary cancer center in South India between January 1, 2010 and December 31, 2013. Among the 60 patients, the primary site of cancer was the larynx in 43 patients and hypopharynx in the remaining 17. All patients had undergone a primary TEP insertion, 55 in the upfront setting and five in the salvage (post-radiation/chemo-radiation) setting. The ability to retain a successful trachea-esophageal speech on follow-up (median 15.5 months) in our series was around 82%. The mean device life of voice prosthesis in our patient cohort was 16 months. There was surprisingly no significant difference in the prosthesis device life on correlation with age, co-morbidities, habitat, literacy status, pre-operative tracheostomy, setting of surgery, and the extent of surgery. Our series has successfully demonstrated the safety and feasibility of using primary TEP coupled with the use of voice prosthesis for voice rehabilitation in properly selected and motivated patients of advanced laryngeal and hypopharyngeal carcinomas across all clinical settings. A mean device life of 16 months makes prosthetic voice rehabilitation, an attractive as well as a financially viable option for patients in a resource constrained setting.

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Microbial colonization of Provox voice prosthesis in the Indian scenario

Abstract: Candida is the most common organism grown on voice prosthesis in Indian scenario. Consumption of curd and history of prior radiotherapy significantly affect Provox prosthesis lifespan.

Cited by 5 publications

References 15 publications

Biofilm Growth Causes Damage to Silicone Voice Prostheses in Patients after Surgical Treatment of Locally Advanced Laryngeal Cancer

Biofilm Growth Causes Damage to Silicone Voice Prostheses in Patients after Surgical Treatment of Locally Advanced Laryngeal Cancer

Precision Antifungal Treatment Significantly Extends Voice Prosthesis Lifespan in Patients Following Total Laryngectomy

Analysis of Factors Affecting the Longevity of Voice Prosthesis Following Total Laryngectomy with a Review of Literature

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