Microbial changes in patients with acute periodontal abscess after treatment detected by PadoTest

Eguchi, Toru; Koshy, Geena; Umeda, Makoto; Iwanami, Tomotoshi; Suga, Jennifer M.; Nomura, Yasuo; Kawanami, Masamitsu; Ishikawa, Isao

doi:10.1111/j.1601-0825.2007.01370.x

Cited by 17 publications

(13 citation statements)

References 31 publications

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“…In the current study, testing for A.a. was performed with two different commercially available tests. The first microbiological assay is a commercially available oligonucleotide probe test that has been applied in a series of scientific studies [24,[26][27][28][29]. The probe of this assay is complementary to conserved regions of the 16S rRNA gene, which encodes the rRNA that forms the small subunit of the bacterial ribosome.…”

Section: Discussionmentioning

confidence: 99%

Comparison of two different microbiological test kits for detection of periodontal pathogens

Cosgarea

Bäumer

Pretzl

et al. 2010

Acta Odontologica Scandinavica

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Section: Discussionmentioning

confidence: 99%

Comparison of two different microbiological test kits for detection of periodontal pathogens

Cosgarea

Bäumer

Pretzl

et al. 2010

Acta Odontologica Scandinavica

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“…Eguchi et al. compared irrigation with sterile physiological saline and 2% minocycline hydrochloride ointment vs. irrigation with sterile physiological saline without the local antibiotic, in 91 patients for 7 days.…”

Section: Abscesses In the Periodontiummentioning

confidence: 99%

“…The most prevalent bacterial species identified in periodontal abscesses, using culture-based or molecular-based diagnostic techniques, is Porphyromonas gingivalis, with a range in prevalence of 50-100% (82,123,128,149,224,321,327) (Fig. 5).…”

Section: Microbiological Findingsmentioning

confidence: 99%

“…Herrera et al (129) compared azithromycin (500 mg, once per day for 3 days) vs. amoxicillin plus clavulanate (500 + 125 mg, three times daily for 8 days), with delayed scaling (after 12 days), in 29 patients with abscesses followed for 1 month, and concluded that both protocols were similarly effective. Eguchi et al (82) compared irrigation with sterile physiological saline and 2% minocycline hydrochloride ointment vs. irrigation with sterile physiological saline without the local antibiotic, in 91 patients for 7 days.…”

Section: Control Of the Acute Conditionmentioning

confidence: 99%

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Acute periodontal lesions

Herrera¹,

Alonso²,

Arriba³

et al. 2014

Periodontology 2000

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This is a review and update on acute conditions affecting the gingival tissues, including abscesses in the periodontium, necrotizing periodontal diseases, and other acute conditions that cause gingival lesions with acute presentation, such as infectious processes not associated with oral bacterial biofilms, muco--cutaneous disorders, and traumatic and allergic lesions. A periodontal abscess is clinically important since it is a relatively frequent dental emergency, it can compromise the periodontal prognosis of the affected tooth, and because bacteria within the abscess can spread and cause infections in other body sites. Different types of abscesses have been identified, mainly by the type of etiology, and there are clear differences between those affecting a previously existing periodontal pocket and those affecting healthy sites. Therapy for this acute condition consists of drainage and tissue debridement, with individual evaluation of the need for systemic antimicrobial therapy. The definitive treatment of the pre--existing condition should be accomplished after the acute phase is controlled.

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“…Periodontal treatment consists of two sessions at oneweek intervals of supragingival scaling and oral hygiene instructions, followed by subgingival scaling and root planing under local anesthesia performed within a period of 14 days, with or without use of antibiotics; however, systemic antibiotics do not act on osteoclasts directly to prevent or suppress bone resorption (Eguchi et al, 2008). Recently, many plants and their extracts have been recognized as useful sources for the prevention and treatment of bone-related disorders, including periodontal disease.…”

Section: Introductionmentioning

confidence: 99%

The impact of compounds isolated from Ocimum sp. on apoptotic activity of osteoclast

Juíz¹,

Gambari²,

Piva³

et al. 2016

J. Med. Plants Res.

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Periodontal disease has multifactorial etiology. The immune response to the microbial challenge leads to osteoclast activation and resorption of the alveolar bone, resulting in tooth loss. Compounds isolated from Ocimum americanum and Ocimum basilicum were analyzed for apoptotic activity towards osteoclast in this study. Steam distillation was used for the extraction of essential oils (EOs) from dry leaves and flowers. The assessment of apoptosis in osteoclasts was carried out through the TUNEL assay and immunocytochemistry for the Fas receptor. The chemical profile of EOs, characterized through gas chromatography-mass spectrometry analysis, revealed methyl cinnamate (O. americanum), linalool, caryophyllene, 1,8-cineole (O. basilicum) as major components. The results showed that essential oils were not able to induce apoptosis in osteoclast; however, linalool (50 to 300 μg.ml -1 ) induced 75% of apoptotic osteoclasts at non-toxic concentrations and the apoptotic activity was confirmed by the increasing levels of Fas receptor on osteoclasts treated with this compound. This study suggests that linalool could be used to control osteoclast activity.

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Microbial changes in patients with acute periodontal abscess after treatment detected by PadoTest

Abstract: Topical treatment with minocycline in pockets with acute periodontal abscess was effective in reducing the bacterial counts as shown by the microbiological investigation using PadoTest 4.5.

Cited by 17 publications

References 31 publications

Comparison of two different microbiological test kits for detection of periodontal pathogens

Comparison of two different microbiological test kits for detection of periodontal pathogens

Acute periodontal lesions

The impact of compounds isolated from Ocimum sp. on apoptotic activity of osteoclast

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