“…periosteal or endosteal areas or in the proximity of Haversian canals) an average value for HI was assigned. According to literature data (Hackett, 1981;Bell, 1990;Jans et al, 2002;Turner-Walker and Syversen, 2002;Jans et al, 2004;Fernández-Jalvo et al, 2010;Müller et al, 2011) MFD was described as non-Wedl and Wedl foci. Non-Wedl MFD is characterised by areas of high concentration of micro-channels and pores, up to 2 μm in diameter, surrounded by a hyper-mineralised rim, due to dissolution and re-precipitation of bone apatite with a higher density (showing a lighter grey tone on SEM-BSE images) with respect to the surrounding bone, caused by bacterial activity.…”