Microbe-mediated Synthesis of Zinc Oxide Nanoparticles and Its Biomedical Applications

Agarwal, Happy; Nakara, Amatullah; Menon, Soumya; Shanmugam, Vijayakumar

doi:10.4324/9780429276330-9

Cited by 3 publications

(4 citation statements)

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“…The protein corona has serum proteins acting as a ligand for the M2 macrophage receptors. It is reported that nanoparticles rapidly uptake M2 macrophages which show anti-inflammatory effect than M1 macrophages [1].…”

Section: Anti-inflammatory Actionmentioning

confidence: 99%

“…Sometimes the persistence of inflammatory action itself may lead to more tissue destruction in the host. Macrophages and neutrophils play a crucial role in regulating inflammation in the pathogenesis of various diseases [1]. Mechanisms that are involved mainly in inflammatory process are prostaglandins released by cyclooxygenase (COX) and nitric oxide production (NO) by nitric oxide synthase [2].…”

Section: Introductionmentioning

confidence: 99%

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Anti-Inflammatory Activity of Dried Ginger Mediated Iron Nanoparticles

Ganta

Jeevitha

Preetha

et al. 2020

JPRI

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Nanotechnology is a branch of science and technology relating to the matter on the atomic and molecular scale in the size range between 1-100 nm. Iron nanoparticles have diverse diagnostic and potential therapeutic applications with unique magnetic and catalytic properties and potent biological activities. The present study aimed to analyse the anti-inflammatory activity of iron nanoparticles synthesized from dried ginger. The synthesized iron nanoparticles were characterized using UV-vis spectroscopy and evaluated for anti-inflammatory activity by inhibition of albumin denaturation assay. The nanoparticles showed maximum absorbance at 360 nm and revealed potent anti-inflammatory effect with maximum of 83.5% inhibition at lowest concentration of 50 µl and thus can be used as an anti-inflammatory agent in various inflammatory diseases.

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Section: Anti-inflammatory Actionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Anti-Inflammatory Activity of Dried Ginger Mediated Iron Nanoparticles

Ganta

Jeevitha

Preetha

et al. 2020

JPRI

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“…ZnO NPs also have outstanding antibacterial, antimicrobial, and UV-blocking properties. Zinc is commonly recognized as an important trace element that can be found in all body tissues, including the brain, muscle, bone, and skin [18][19][20]. Zinc participates in the body's metabolism and plays important roles in protein and nucleic acid synthesis, hematopoiesis, and neurogenesis as the key component of various enzyme systems.…”

Section: Introductionmentioning

confidence: 99%

Anti-Inflammatory and Antifungal Activity of Zinc Oxide Nanoparticle Using Red Sandalwood Extract

Yuvaraj¹,

Priyadharshini²,

Kumar³

et al. 2023

Pharmacophore

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Pterocarpus santalinus is valued for its strong, dark-purple, bitter heartwood. The gentle aroma of P. santalinus heartwood is caused by the presence of terpenoids, which gives it its color and fragrance. P. santalinus heartwood dye is used as a light microscopy stain, and as a coloring agent in pharmaceutical preparations. The Antibacterial, antimicrobial, and UV-blocking capabilities of ZnO NPs are outstanding compared with other metal oxides. The study aims to analyze the antiinflammatory and antifungal activity of zinc oxide nanoparticles using red sandalwood extract. A plant extract sample was taken and 100ml of distilled water was added. Heated at 50°C for 5-10 minutes. The heated solution was filtered. .0.861g of zinc oxide was measured and dissolved in 70 ml of distilled water. The mixture was transferred to extract the sample. The solution was heated and labeled. The heating mantle was used with a temperature of 50-60°C and the time took was 6-8 minutes. The results obtained were statistically analyzed using spearman correlation analysis and using SPSS software. The sample shows an increasing absorbance rate and increases in the zone of inhibition with the increase in the concentration of the extract. It also showed an effective antifungal activity against C.albicans. The correlation analysis is statistically significant with p value<0.05. From the present study, it is concluded that red sandal-mediated zinc oxide nanoparticles possess anti-inflammatory and antifungal activity.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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“…Zinc is commonly recognized as an important trace element that can be found in all body tissues, including the brain, muscle, bone, and skin. [18][19][20] Zinc participates in the body's metabolism and plays important roles in protein and nucleic acid synthesis, hematopoiesis, and neurogenesis as the key component of various enzyme systems. Because of the small particle size of Nano-ZnO, zinc is more readily absorbed by the body.…”

Section: Introductionmentioning

confidence: 99%

Anti inflammatory and antifungal activity of zinc oxide nanoparticle using red sandalwood extract

2023

JPTCP

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Introduction : Pterocarpus santalinus is valued for its strong, dark-purple, bitter heartwood. The gentle aroma of P. santalinus heartwood is caused by the presence of terpenoids, which gives it its color and fragrance. P. santalinus heartwood dye is used as a light microscopy stain, and as a coloring agent in pharmaceutical preparations. Antibacterial, antimicrobial, and UV-blocking capabilities of ZnO NPs are outstanding compared with other metal oxides. The aim of the study is to analyse the antiinflammatory and antifungal activity of zinc oxide nanoparticles using red sandal wood extract. Materials And Methods: A plant extract sample was taken and 100ml of distilled water was added. Heated at 50°C for 5-10 minutes. The heated solution was filtered. .0.861g of zinc oxide was measured and dissolved in 70 ml of distilled water. The mixture was transferred to extract the sample. The solution was heated and labeled. The heating mantle was used with a temperature of 50-60°C and the time taken was 6-8 minutes. The results obtained were statistically analyzed using spearman correlation analysis and using SPSS software. Results:The sample shows an increasing absorbance rate and increase in the zone of inhibition with the increase in the concentration of the extract. It also showed an effective antifungal activity against C.albicans. The correlation analysis is statistically significant with p value<0.05. Conclusion :From the present study, it is concluded that red sandal mediated zinc oxide nanoparticles possess anti-inflammatory and antifungal activity.

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Microbe-mediated Synthesis of Zinc Oxide Nanoparticles and Its Biomedical Applications

Cited by 3 publications

References 1 publication

Anti-Inflammatory Activity of Dried Ginger Mediated Iron Nanoparticles

Anti-Inflammatory Activity of Dried Ginger Mediated Iron Nanoparticles

Anti-Inflammatory and Antifungal Activity of Zinc Oxide Nanoparticle Using Red Sandalwood Extract

Anti inflammatory and antifungal activity of zinc oxide nanoparticle using red sandalwood extract

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