Microarray biochip fabricated on silicon nanowires/carbon dots heterostructures for enhanced viral DNA detection

Gogianu, Larisa; Popescu, Marian C.; Vasile, Bogdan S.; Mihalache, Iuliana; Anghel, Elena M.; Damian, Celina M.; Salceanu, Alexandru; Boldeiu, Adina; Constantin, Elena; Radoi, Antonio; Simion, Monica; Popescu, Melania A.

doi:10.1016/j.apsusc.2023.157878

Cited by 5 publications

(1 citation statement)

References 69 publications

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“…Gogianu et al presented a proof-of-concept for an advanced microarray platform designed to enhance DNA detection [ 178 ]. In this study, three-dimensional microarray chips were fabricated using metal-assisted chemical etching on silicon nanowire substrates, subsequently coated with SU-8 polymer and further modified with carbon quantum dots (CDs) in either poly (dimethyldiaminomethane acrylate) (PDDA) or polyethyleneimine (PEI) solutions.…”

Section: Dna Nanotechnology-enabled Biosensor For Virus Detectionmentioning

confidence: 99%

Recent Advances in DNA Nanotechnology-Enabled Biosensors for Virus Detection

2023

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Virus-related infectious diseases are serious threats to humans, which makes virus detection of great importance. Traditional virus-detection methods usually suffer from low sensitivity and specificity, are time-consuming, have a high cost, etc. Recently, DNA biosensors based on DNA nanotechnology have shown great potential in virus detection. DNA nanotechnology, specifically DNA tiles and DNA aptamers, has achieved atomic precision in nanostructure construction. Exploiting the programmable nature of DNA nanostructures, researchers have developed DNA nanobiosensors that outperform traditional virus-detection methods. This paper reviews the history of DNA tiles and DNA aptamers, and it briefly describes the Baltimore classification of virology. Moreover, the advance of virus detection by using DNA nanobiosensors is discussed in detail and compared with traditional virus-detection methods. Finally, challenges faced by DNA nanobiosensors in virus detection are summarized, and a perspective on the future development of DNA nanobiosensors in virus detection is also provided.

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Section: Dna Nanotechnology-enabled Biosensor For Virus Detectionmentioning

confidence: 99%

Recent Advances in DNA Nanotechnology-Enabled Biosensors for Virus Detection

2023

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Intelligent point of care testing for medicine diagnosis

Gao,

2024

Interdisciplinary Medicine

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Intelligent point‐of‐care testing (iPOCT) is a rapidly advancing technology that combines molecular detection and bio‐sensing techniques to achieve instant and accurate analysis through advanced sensors and intelligent algorithms. Molecular detection technologies, such as nucleic acid isothermal amplification, biochip and microfluidics, enable rapid analysis of the chemical composition and concentration of samples, thereby determining their presence. Bio‐sensing technology utilizes the recognition properties of biomolecules in conjunction with sensors to detect specific biomolecules or biological processes. iPOCT technology holds broad prospects for application in the field of healthcare and is expected to enhance detection sensitivity, accuracy, and intelligence through further development. In this review, we delineate the developmental journey of iPOCT, followed by a discussion on the principles of molecular detection and bio‐sensing technology, as well as the design of iPOCT devices for health monitoring and disease diagnosis. Furthermore, we showcased illustrative examples of iPOCT applications in disease diagnosis, highlighting the integration of iPOCT technology with wearable devices and smartphones for attaining more precise and personalized diagnostic results.

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The Notability of Silicon Nanowires in Optoelectronic, Environment and Health

Rahmani,

Zaïbi

2024

Silicon

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Microarray biochip fabricated on silicon nanowires/carbon dots heterostructures for enhanced viral DNA detection

Cited by 5 publications

References 69 publications

Recent Advances in DNA Nanotechnology-Enabled Biosensors for Virus Detection

Recent Advances in DNA Nanotechnology-Enabled Biosensors for Virus Detection

Intelligent point of care testing for medicine diagnosis

The Notability of Silicon Nanowires in Optoelectronic, Environment and Health

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