Microalgae as sources of omega-3 polyunsaturated fatty acids: Biotechnological aspects

Barta, Gabriel; Coman, Virginia; Vodnar, Dan Cristian

doi:10.1016/j.algal.2021.102410

Cited by 68 publications

(30 citation statements)

References 167 publications

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“…Omega-3 acids, which are made up of two types of unsaturated fatty acids called EPA and DHA [26], were employed in this study, and they were given to one group prophylactically before causing the wound, and to another group before and after executing the wound. The researchers compared the treated groups and the treatment periods of 3 and 7 days afterincision done.…”

Section: Discussionmentioning

confidence: 99%

Histopathological and Scores Assessment of Using Omega-3 for Improvement Gingival Wound Healing Process in Rabbit Model

Mahmoud

Mammdoh

Saeed

2022

Egyptian Journal of Veterinary Sciences

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Section: Discussionmentioning

confidence: 99%

Histopathological and Scores Assessment of Using Omega-3 for Improvement Gingival Wound Healing Process in Rabbit Model

Mahmoud

Mammdoh

Saeed

2022

Egyptian Journal of Veterinary Sciences

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“…Moreover, PUFAs are associated with decreased neuron inflammation and apoptosis. There is also evidence that omega-3 PUFAs play a critical role in psychiatric health, pathophysiology of neurodegenerative disorders such as Alzheimer’s disease and the protection of the neuron membrane [ 55 , 57 ].…”

Section: Therapeutic Potential Of Microalgae In Sleep and Mood Regula...mentioning

confidence: 99%

Potential Psychoactive Effects of Microalgal Bioactive Compounds for the Case of Sleep and Mood Regulation: Opportunities and Challenges

2022

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Sleep deficiency is now considered an emerging global epidemic associated with many serious health problems, and a major cause of financial and social burdens. Sleep and mental health are closely connected, further exacerbating the negative impact of sleep deficiency on overall health and well-being. A major drawback of conventional treatments is the wide range of undesirable side-effects typically associated with benzodiazepines and antidepressants, which can be more debilitating than the initial disorder. It is therefore valuable to explore the efficiency of other remedies for complementarity and synergism with existing conventional treatments, leading to possible reduction in undesirable side-effects. This review explores the relevance of microalgae bioactives as a sustainable source of valuable phytochemicals that can contribute positively to mood and sleep disorders. Microalgae species producing these compounds are also catalogued, thus creating a useful reference of the state of the art for further exploration of this proposed approach. While we highlight possibilities awaiting investigation, we also identify the associated issues, including minimum dose for therapeutic effect, bioavailability, possible interactions with conventional treatments and the ability to cross the blood brain barrier. We conclude that physical and biological functionalization of microalgae bioactives can have potential in overcoming some of these challenges.

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“…EPA consumption on a regular basis helps to diminish the risk of stroke, cardiovascular and neurological illnesses, rheumatoid arthritis, and other biological threats [ 3 ]. Microalgae are primary sources of EPA recognized as virtually essential omega-3 PUFAs [ 4 ]. Nannochloropsis oceanica ( N .…”

Section: Introductionmentioning

confidence: 99%

Kinetic and thermodynamic studies of eicosapentaenoic acid extraction from Nannochloropsis oceanica using tetramethyl ammonium chloride and microwave irradiation

et al. 2022

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Microalgae have garnered widespread attention as a sustainable source of pharmaceuticals and nutraceuticals. As for extracting lipids from microalgae, the combination of microwave-assisted extraction (MAE) and ionic liquids (IL) is shown to be promising. However, such an undertaking usually requires a large consumption of expensive ILs. This study innovatively employs tetramethyl ammonium chloride ([TMAm][Cl]) as an additive in water medium to associate with microwave-assisted ionic liquid extraction (MAILE) in extracting lipids from Nannochloropsis oceanica (N. oceanica) microalgae. In extraction, knowledge of reaction kinetics is crucial since it provides the foundation for developing, controlling, and improving the processes of extraction. Herein, using MAILE, lipids are extracted from N. oceanica microalgae and transesterified to eicosapentaenoic acid (EPA). Mass transfer kinetics are, therefore, investigated using the first and second-order rate law and Patricelli’s model. In the development of models, the influence of temperature (60–90°C) and reaction time (1–25 min) on EPA extraction is empirically evaluated. From the thermodynamic study, the positive values of ΔS (+0.10 kJ mol-1K-1) and ΔH (+32.50 kJ mol-1) and the negative value of ΔG (-1.68 to -4.75 kJ mol-1) confirm that this process is endothermic in nature, irreversible and spontaneous. MAILE proves to be a promising approach for the extraction of high-quality EPAs. Due to its low cost, rapid operation, and environmental friendliness, it is seen to be suitable for both pharmaceutical and nutraceutical applications.

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Microalgae as sources of omega-3 polyunsaturated fatty acids: Biotechnological aspects

Cited by 68 publications

References 167 publications

Histopathological and Scores Assessment of Using Omega-3 for Improvement Gingival Wound Healing Process in Rabbit Model

Histopathological and Scores Assessment of Using Omega-3 for Improvement Gingival Wound Healing Process in Rabbit Model

Potential Psychoactive Effects of Microalgal Bioactive Compounds for the Case of Sleep and Mood Regulation: Opportunities and Challenges

Kinetic and thermodynamic studies of eicosapentaenoic acid extraction from Nannochloropsis oceanica using tetramethyl ammonium chloride and microwave irradiation

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