Microalbuminuria in diabetes mellitus: Association with age, sex, weight, and creatinine clearance

Abstract

Studies in the Western literature show a linear relationship between degree of microalbuminuria and body mass index (BMI), blood pressure, and duration of diabetes. This study was aimed to determine the correlation of microalbuminuria with age, sex, duration of diabetes, BMI, and creatinine clearance in type-2 diabetics in Indian population. One hundred patients (59 males and 41 females) with type-2 diabetes mellitus of duration six months or more and negative for albumin in urine by albustic method were included in the study. Detailed clinical history was taken followed by a thorough physical examination that included neurological examination in the selected patients. Micral test was used for estimation of microalbuminuria. Overall prevalence of microalbuminuria in the present study was 37%. Among the patients with microalbuminuria, 20 were males and 17 were females. Pearson correlation of microalbuminuria with age showed statistically significant linear relationship. Gender-wise correlation analysis of microalbuminuria failed to show any statistical significance. Correlation of microalbuminuria with BMI was also not significant (r = 0.063, P > 0.05). Creatinine clearance negatively correlated with microalbuminuria, but this was statistically insignificant. There was a statistically significant correlation of microalbuminuria with duration of diabetes. Prevalence of microalbuminuria is around 37% in type-2 diabetes mellitus. Incidence of microalbuminuria increases with age as well as with increased duration of diabetes mellitus. There is no effect of BMI and sex on the prevalence of microalbuminuria.

Microalbuminuria in Patients with Diabetes Mellitus: Prevalence and Associated Risk factors Title of your

“…This variation in the prevalence of MAU rate can be attributed to several factors such as: Differences in populations, variability in the sample size, difference in the degree of glycemic control, the definition of MAU, the methods of measurement of MAU and urine collection, and the stage of the disease and ethnicity [18]. In present study obesity had highly significant association with MAU, which is in agreement with Moroccan study (Habbal et al) [19], while there was no relation between positive MAU and obesity in an Indian study [20].…”

Correlation Between Microalbuminuria and Hba1c Among Type2 Diabetic Patients in Jammu, J and K State, India.

“…7 In the present study, the prevalence of microalbuminaria in Jammu was 59 %, whereas, it has been reported to be 37% in Mangalore by Chowta et al 6 6 , one of the main causes is, " irregular treatment with poor glycemic control and also may be due to the "small sample size" in their study. The sample size in the above report and the present study is almost similar, being 100 and 110 respectively.…”

Correlation of Microalbuminuria With Age, Duration, Glycated Hemoglobin, Blood Sugar Levels, Blood Pressure and Renal Parameters of Type 2 Diabetes Patients

“…Similar studies have also shown negative correlation with microalbuminuria [15][16][17]. Gender-wise significance has seen in creatinine clearance.…”