Micro-scale Synthesis andIn-SituSpectroscopic Characterization of Some Chemical Weapons Related Organophosphonate Compounds

Gas chromatography/mass spectrometric analysis of methyl esters of N,N‐dialkylaminoethane‐2‐sulfonic acids for verification of the Chemical Weapons Convention

“…Since gas chromatography coupled with mass spectrometry (GC/ MS) is the widely used technique for identification of CWCrelated compounds, [17][18][19][20] a great deal of work is devoted to the development of a mass spectral database of these compounds. 8,9,[21][22][23][24] The chemicals relevant to the convention are enlisted in three schedules of an annex of the CWC. The categorization of chemicals in the three schedules is based on the toxicity, past use as CWAs, and commercial applicability of chemicals.…”

“…A laboratory can become and stay designated, by showing its performance in PTs, which essentially requires availability of spectral data of CWC‐related compounds and sample preparation, analytical skills, judgment and reporting. Since gas chromatography coupled with mass spectrometry (GC/MS) is the widely used technique for identification of CWC‐related compounds,17–20 a great deal of work is devoted to the development of a mass spectral database of these compounds 8, 9, 21–24. The chemicals relevant to the convention are enlisted in three schedules of an annex of the CWC.…”

Gas chromatography/mass spectrometric analysis of N,N‐dialkylaminoethyl‐2‐chlorides and trimethylsilyl derivatives of N,N‐dialkylaminoethan‐2‐ols for verification of the Chemical Weapons Convention

“…Since gas chromatography coupled with mass spectrometry (GC/MS) is the most widely used technique for identification of CWC-related compounds (CRCs), [17][18][19][20] a great deal of work has been devoted to the development of a GC/MS database of these compounds. 8,9,[21][22][23][24] The chemicals of significance are listed in three schedules of an annex of the CWC. The categorization of the chemicals is based on their toxicity, past use as CWAs, and their commercial applicability.…”

Study of electron ionization mass spectra of bis(trimethylsilyl) esters of alkylphosphonic and alkylthiophosphonic acids

“…2,3 For unambiguous identification of CRCs, the OPCW maintains a network of designated laboratories by conducting official proficiency tests to evaluate their analytical capabilities. [4][5][6][7] Chemicals considered to be a potential risk to the convention are listed in an Annex to the CWC under three schedules. 8,9 Alkyl (methyl, ethyl, n-propyl and isopropyl)phosphosphonic acids (APAs) and their thio analogues, i.e.…”