Micro RNA mediated regulation of nutrient response in plants: the case of nitrogen

Jagadhesan, B.; Das, Samrat; Singh, D. V.; Jha, Shailendra K.; Kumar, Dilip; Sathee, Lekshmy

doi:10.1007/s40502-022-00653-0

Cited by 6 publications

(2 citation statements)

References 116 publications

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“…miRNAs have emerged as important regulators of plant stress responses and for maintaining nutrient homeostasis by regulating the expression of transporters involved in nutrient absorption and mobilization ( Paul et al, 2015 ). miRNAs also have a role in nutritional homeostasis by acting as an endogenous signal for micro and macronutrient availability ( Marín-González and Suárez-López, 2012 ; Kehr, 2013 ; Jagadhesan et al, 2022 ). The reports on miRNAs regulating micronutrient homeostasis in legumes are meager, barring the information pertaining to Phaseolus vulgaris (common bean) and Medicago truncatula ( Valdes-Lopez et al, 2010 ; Naya et al, 2014 ).…”

Section: Exploitation Of Mirnas For Micronutrient Enhancementmentioning

confidence: 99%

Integrated breeding approaches to enhance the nutritional quality of food legumes

Jha

Yadav²,

Raiya³

et al. 2022

Front. Plant Sci.

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Global food security, both in terms of quantity and quality remains as a challenge with the increasing population. In parallel, micronutrient deficiency in the human diet leads to malnutrition and several health-related problems collectively known as “hidden hunger” more prominent in developing countries around the globe. Biofortification is a potential tool to fortify grain legumes with micronutrients to mitigate the food and nutritional security of the ever-increasing population. Anti-nutritional factors like phytates, raffinose (RFO’s), oxalates, tannin, etc. have adverse effects on human health upon consumption. Reduction of the anti-nutritional factors or preventing their accumulation offers opportunity for enhancing the intake of legumes in diet besides increasing the bioavailability of micronutrients. Integrated breeding methods are routinely being used to exploit the available genetic variability for micronutrients through modern “omic” technologies such as genomics, transcriptomics, ionomics, and metabolomics for developing biofortified grain legumes. Molecular mechanism of Fe/Zn uptake, phytate, and raffinose family oligosaccharides (RFOs) biosynthesis pathways have been elucidated. Transgenic, microRNAs and genome editing tools hold great promise for designing nutrient-dense and anti-nutrient-free grain legumes. In this review, we present the recent efforts toward manipulation of genes/QTLs regulating biofortification and Anti-nutrient accumulation in legumes using genetics-, genomics-, microRNA-, and genome editing-based approaches. We also discuss the success stories in legumes enrichment and recent advances in development of low Anti-nutrient lines. We hope that these emerging tools and techniques will expedite the efforts to develop micronutrient dense legume crop varieties devoid of Anti-nutritional factors that will serve to address the challenges like malnutrition and hidden hunger.

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Section: Exploitation Of Mirnas For Micronutrient Enhancementmentioning

confidence: 99%

Integrated breeding approaches to enhance the nutritional quality of food legumes

Jha

Yadav²,

Raiya³

et al. 2022

Front. Plant Sci.

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“…Researchers have also studied N-responsive miRNAs in bread wheat and durum wheat [21][22][23][24][25] . Several miRNAs associated with N deficiency response and NUE are reported in crop plants 26,27 . One of the N-regulated conserved miRNA, miR169a, targets transcription factor NFYA and overexpression of miR169a reduces N uptake due to suppression of nitrate transporters NPF6.3 and NRT2.1 28 .…”

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confidence: 99%

Long term nitrogen deficiency alters expression of miRNAs and alters nitrogen metabolism and root architecture in Indian dwarf wheat (Triticum sphaerococcum Perc.) genotypes

Das

Singh

Meena

et al. 2023

Sci Rep

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The important roles of plant microRNAs (miRNAs) in adaptation to nitrogen (N) deficiency in different crop species especially cereals (rice, wheat, maize) have been under discussion since last decade with little focus on potential wild relatives and landraces. Indian dwarf wheat (Triticum sphaerococcum Percival) is an important landrace native to the Indian subcontinent. Several unique features, especially high protein content and resistance to drought and yellow rust, make it a very potent landrace for breeding. Our aim in this study is to identify the contrasting Indian dwarf wheat genotypes based on nitrogen use efficiency (NUE) and nitrogen deficiency tolerance (NDT) traits and the associated miRNAs differentially expressed under N deficiency in selected genotypes. Eleven Indian dwarf wheat genotypes and a high NUE bread wheat genotype (for comparison) were evaluated for NUE under control and N deficit field conditions. Based on NUE, selected genotypes were further evaluated under hydroponics and miRNome was compared by miRNAseq under control and N deficit conditions. Among the identified, differentially expressed miRNAs in control and N starved seedlings, the target gene functions were associated with N metabolism, root development, secondary metabolism and cell-cycle associated pathways. The key findings on miRNA expression, changes in root architecture, root auxin abundance and changes in N metabolism reveal new information on the N deficiency response of Indian dwarf wheat and targets for genetic improvement of NUE.

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The Role of microRNA in Stress Signaling and Adaptive Response in Plants

Tiwari

2024

Stress Biology in Photosynthetic Organisms

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Micro RNA mediated regulation of nutrient response in plants: the case of nitrogen

Cited by 6 publications

References 116 publications

Integrated breeding approaches to enhance the nutritional quality of food legumes

Integrated breeding approaches to enhance the nutritional quality of food legumes

Long term nitrogen deficiency alters expression of miRNAs and alters nitrogen metabolism and root architecture in Indian dwarf wheat (Triticum sphaerococcum Perc.) genotypes

The Role of microRNA in Stress Signaling and Adaptive Response in Plants

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