Micro-Nano Technologies for Cell Manipulation and Subcellular Monitoring

Lopez-Martinez, Maria J.; Campo, Eva M.

doi:10.5772/20038

Cited by 2 publications

(2 citation statements)

References 50 publications

(46 reference statements)

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“…A key aspect of TOC analysis is the use of extraction and ejection tools and methods for cell and subcellular organelles [85][86][87]. Tools for cell manipulation emerged at the same time cell and tissue studies began and their implementation has been and continues to be crucial for conducting certain TOC studies [87][88][89] .…”

Section: Mass Spectrometrymentioning

confidence: 99%

“…Tools for cell manipulation emerged at the same time cell and tissue studies began and their implementation has been and continues to be crucial for conducting certain TOC studies [87][88][89] . In TOC analysis, nanopipettes are some of the most used probing tools [85,86,[88][89][90]. Currently there are two commonly used methods for extracting intracellular chemistry and both use specialized micro and nano probes [88,89].…”

Section: Mass Spectrometrymentioning

confidence: 99%

See 1 more Smart Citation

True One Cell Chemical Analysis in Cancer Research: A Review

Reyes

Verbeck

2023

J. Anal. Oncol.

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True One Cell (TOC) analysis Is becoming highly critical for functional studies of cancer cells. This is partially because it is the only form of analysis that provides an avenue for studying the heterogeneity and cell-to-cell variations of individual cancer cells, thus providing unique insight into complex regulatory processes that govern TOC functions within a tumor. Additionally, true one cell techniques are playing an increasingly important role in current attempts to implement TOC metabolomic and proteomic studies, as well as emerging attempts to spatially resolve TOC information. In this review we provide a brief overview of the basis of the field and discuss its applications in TOC metabolomics and proteomics.

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