Micro-colonization of the denture-fitting surface by Candida albicans

Allison, R.T.; Douglas, William H.

doi:10.1016/0300-5712(73)90059-6

Cited by 52 publications

(33 citation statements)

References 4 publications

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“…One of the earliest papers to compare the relationship among C. albicans, acrylic resin, and soft-lining materials showed that, in three subjects, soft-lining materials supported the growth of C. albicans in vivo, with a thicker plaque being present than on the surface of heat-cured acrylic resin (Allison and Douglas, 1973). Subsequent work was undertaken on yeast colonization on heatcured maxillary dentures and soft-lined mandibular dentures in 39 patients attending a dental school clinic (Makila and Hopsu-Hava, 1977).…”

Section: (33) In Vivo Investigations Of Colonization By C Albicans mentioning

confidence: 99%

Denture Plaque and Adherence of Candida Albicans To Denture-Base Materials in Vivo and in Vitro

Radford

Challacombe

Walter

1999

Critical Reviews in Oral Biology & Medicine

298

249

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The aim of this paper is to review our understanding of the mechanisms and clinical significance of adhesion of C. albicans to denture-base materials in relation to denture plaque and denture-related stomatitis. Earlier reports in the literature of a 65% prevalence level of denture-related stomatitis seem to be exaggerated. More recent studies indicate that denture-related stomatitis is considerably less common, particularly in normal healthy subjects. The etiology of the condition is discussed in this review, and although much of the literature supports the view that the condition is strongly associated with C. albicans, this is not always so. In some subjects, the cause appears to be related to a non-specific plaque. This review also considers the role of denture plaque in the pathogenesis of denture-related stomatitis, the sequential development of denture plaque, and its colonization by Candida organisms. Designing controlled in vivo studies is difficult, and as a consequence, many investigators have had to resort to in vitro studies. The majority of these studies have attempted to investigate the hydrophobicity of C. albicans, relating the surface free-energy of denture-base materials, particularly acrylic resin, to that of the organism. Surprisingly little work has been directed at surface roughness and how it affects retention of organisms. Further, no attention has been paid to the properties and character of the surface, other than average surface roughness, as it affects adhesion. A comparison of results from in vitro studies on the effect on adhesion of pre-coating the surfaces of denture-base materials with saliva has produced equivocal conclusions. This is largely due to little standardization of experimental protocols between studies, particularly in the collection and handling of the saliva used. In conclusion, the review strongly supports the suggestion that adherence of C. albicans to denture-base materials in vitro is related to the hydrophobicity of the organism. The clinical significance of the observation and the mechanisms for the development and maturation of denture plaque are yet to be understood. There is a clear need for further investigation of other factors that may moderate the adhesion of organisms and subsequent colonization of denture-base materials.

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Section: (33) In Vivo Investigations Of Colonization By C Albicans mentioning

confidence: 99%

Denture Plaque and Adherence of Candida Albicans To Denture-Base Materials in Vivo and in Vitro

Radford

Challacombe

Walter

1999

Critical Reviews in Oral Biology & Medicine

298

249

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“…Since the powder component contains no initiator and the liquid no monomer, tissue conditioners are comprised of noncross-linked amorphous polymers 5,11,12) . It has been reported that soft denture liners can be deeply penetrated by Candida albicans 14) , and that these materials promote greater levels of growth and/or colonization of Candida than hard denture base resins [15][16][17] . Hard denture base resins can be cleaned by a combination of mechanical and chemical methods.…”

Section: Introductionmentioning

confidence: 99%

Compatibility of tissue conditioners and denture cleansers: Influence on surface conditions

et al. 2010

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Chemical cleansing by denture cleansers is the first choice for denture plaque control of tissue conditioners. This study evaluated the influences of denture cleansers on the surface quality of tissue conditioners by determining surface roughness and porosity. Three tissue conditioners (Hydro-Cast, SR-Ivoseal, Visco-Gel) and 3 types of denture cleansers (Pika [enzyme type], Polident [neutral peroxide type with enzymes], Steradent [alkaline peroxide type]) were evaluated. Five specimens of each tissue conditioner/solution combination for each time period of immersion were prepared. The surface roughness of dental stone casts made from the tissue conditioners was evaluated using a profilometer. The surface quality of Hydro-Cast and Visco-Gel tended to be most deteriorated by the alkaline peroxide cleanser. The enzyme type of denture cleansers is most suitable for tissue conditioners in terms of surface quality. The suitable period for application of the enzyme cleansers would range from 3 to 7 days.

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“…The loss of surface integrity and surface smoothness may begin three to four days after application 9) . This surface change can irritate denture-bearing areas, and at the same time create an environment for the colonization of oral microorganisms -which can accelerate the deterioration of the tissue conditioner 10,11) . The latter occurs because the materials are easily colonized and deeply infected by these organisms 10,12) .…”

Section: Introductionmentioning

confidence: 99%

“…This surface change can irritate denture-bearing areas, and at the same time create an environment for the colonization of oral microorganisms -which can accelerate the deterioration of the tissue conditioner 10,11) . The latter occurs because the materials are easily colonized and deeply infected by these organisms 10,12) . Against this background, denture cleansers are occasionally used to clean dentures lined with tissue conditioner.…”

Section: Introductionmentioning

confidence: 99%