Micro-Ball Lensed Fiber-Based Glucose Sensor

Harun, Sulaiman Wadi; Jasim, Ali Abdulhadi; Rahman, Husna Abdul; Muhammad, Mohd Zulkifli; Ahmad, Harith

doi:10.1109/jsen.2012.2215958

Cited by 33 publications

(26 citation statements)

References 11 publications

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“…1546 nm to 1553 nm region was chosen for the analysis as it could provide enough absorption features for dye solution that is sufficiently higher and more dominant than the other light intensity attenuation effects occurring in the analyte [14].…”

Section: Sensor Fabrication and Operating Principlementioning

confidence: 99%

Dual Output Approach in Dye Concentrations Determination Using Non-Adiabatic Tapered Fiber

et al. 2015

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A non-adiabatic tapered optical fiber sensor based on interferometric approach was developed by tapering a singlemode fiber using flame brushing technique. Two output variables in the form of absorption and spectral shift were used to infer the dye concentration of an analyte containing Remazol Black B. The system could measure the dye concentration of the analyte within a range of 50 to 250 ppm with sufficient sensitivity and configurability. A sensitivity of 7.61 × 10 −5 abs/ppm and 0.0045 nm/ppm was obtained for the output derived from the absorption of light and spectral shift, respectively. A new predictive model was formulated by combining the predicted dye concentrations of absorption and spectral shift with equal weightings. Then, an experiment was performed to measure the accuracy of the models that use absorption, spectral shift, and their combination to predict the concentration of an analyte in the range of 50 to 250 ppm. The differences between the actual and the predicted dye concentration values were evaluated in terms of the correlation coefficient (R 2 ), root-mean-square error (RMSE), and mean absolute percentage error (MAPE), respectively. The results show that by combining the two parameters, a better estimate (R 2 = 0.9875, RMSE = 7.6761, MAPE = 4.1257) of the dye concentration with higher correlation and lower error can be achieved. Finally, an additional experiment is conducted to validate the accuracy of the sensors.

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Section: Sensor Fabrication and Operating Principlementioning

confidence: 99%

Dual Output Approach in Dye Concentrations Determination Using Non-Adiabatic Tapered Fiber

et al. 2015

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“…Zheng and Li (2010) have demonstrated that MNF tips can be inserted into the nucleus of living MCF-7 cancer cells to detect a biomarker, telomerase. A compact microball lens structure fabricated at the cleaved tip of an MNF coupler was proposed and demonstrated by Harun et al (2013) for sensing various glucose concentrations in deionized water. Plaschke et al (1997) described a new immobilization concept that consists of the encapsulation of dextran-linked fluorescence indicators in an organic hydrogel.…”

Section: Cellular Microenvironment Sensorsmentioning

confidence: 99%

Optical fibres and sensors for biomedical applications

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Brambilla

2015

Biophotonics for Medical Applications

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“…Blood glucose monitoring is required in body fluids to maintain glucose level in diabetes mellitus in which dietary regulations are required [2][3][4][5][6] . Measurement of sugar concentration is also needed in areas like food industries where sugar the sugar levels in juices, other beverages and food items is carried out.…”

Section: Introductionmentioning

confidence: 99%

“…Speckle based non-invasive techniques are also reported for non-invasive measurement of glucose concentration in blood 12,13 . These techniques are based on different principle of measurement having characteristic advantages and disadvantages 2,9 . Sugar level monitors used in food and agricultural products include electronic tongues, Spectroscopic and chromatographic techniques.…”

Section: Introductionmentioning

confidence: 99%

“…Rotation of plane of polarization of linearly polarised light is proportional to the concentration of sugar in the solution. This technique can be used to measure the concentration of glucose when passing through sample especially through aqueous humor of eye where glucose is most likely to present 2,9 . But using a polarizer analyzer pair, commercially available detectors and Malu's law it becomes difficult to determine the change in state of polarization when the concentration of optically active medium under investigation is small.…”

Section: Introductionmentioning

confidence: 99%

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Measurement of concentration of sugar in solutions with laser speckle decorrelation

et al. 2015

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Measurement of rotation of plane of polarization of linearly polarized light can provide information about the concentration of the optically active system with which it interacts. For substances containing sugar, accurate measurement of rotation of linearly polarized light can provide quantitative information about concentration of sugar in the material. Measurement of sugar concentration is important in areas ranging from blood sugar level measurement in body fluids to measurement of sugar concentrations in juices and other beverages. But in many of these cases, the changes introduced to the state of polarization considering a sample of practical proportion is low and the measurement of low optical rotations becomes necessary. So methods with higher sensitivity, accuracy and resolution need to be developed for the measurement of low optical rotations. Here we describe the development of a compact, low cost, field portable, device for rotation sensing leading to sugar concentration measurements, using speckle de-correlation technique. The developed device measures rotations by determining the changes occurring to a speckle pattern generated by a laser beam passing through the medium under investigation. The device consists of a sample chamber, a diode laser module, a ground glass diffuser and a digital sensor for recording of laser speckle patterns. The device was found to have high resolution and sensitivity.

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Micro-Ball Lensed Fiber-Based Glucose Sensor

Cited by 33 publications

References 11 publications

Dual Output Approach in Dye Concentrations Determination Using Non-Adiabatic Tapered Fiber

Dual Output Approach in Dye Concentrations Determination Using Non-Adiabatic Tapered Fiber

Optical fibres and sensors for biomedical applications

Measurement of concentration of sugar in solutions with laser speckle decorrelation

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