Micro-angiography of Normal and Pathologic Human Adrenals in Prenatal and Aging Course

The Nature of the Venous Systems in the Adrenal Gland

“…The chromaffin mass moves within the adrenal cortex with its own blood supply. The microcirculatory pattern then changes throughout foetal life (Sasano et al 1971) but the sinusoids of the cortex remain quite different from those of the phaeochro mocytes (Fig. 6 b).…”

“…Sasano et al (1971) reported difficulty in filling the sinu soids with a barium solution. The 'hold-up of blood at the cortico-medullary vascular dam', referred to by Dobbie and Symington (1966), is an artefact caused by insufficient wash out of red blood cells from the cortical sinusoids.…”

“…1 b and 2 b). The only marked differences between the human and canine venous systems are 1. the presence of an emissary vein in the human 2. the muscular content of the human adrenal vein and 3. a venous communi cation with the liver in the human (Sasano et al 1971). These differences do not concern the current assessment of whether a portal venous system is present in canine and human adrenal glands.…”

Tissue Microvenography of the Adrenal in Cirrhosis with Portal Hypertension

“…The human adrenal venous system is different from that of dog in the following features (Dempster 1974); 1) the presence of an emissary vein, 2) the muscular content, and 3) a venous communication with the liver. Sasano et al (1971) have demonstrated the above venous communication in the right adrenal gland. This study concerns postmortem microvenography of the adrenals in cases with liver cirrhosis, in an attempt to throw light on the adrenl-liver com munication with special reference to changes in the adrenal venous system.…”

Increasing genome instability in adrenocortical carcinoma progression with involvement of chromosomes 3, 9 and X at the adenoma stage

“…However, adrenocortical nodules of 2-3 cm diameter may be found at autopsy in 1.5-8.7% (Lack et al, 1990) of an unselected population. While some of these represent hyperplastic regenerative nodules adjacent to ischaemic atrophic change (Dobbie, 1969;Sasano et al, 1971), many are neoplastic. With the increasing use of sensitive scanning techniques, they are now being identified when patients are investigated for other intraabdominal pathology.…”