“…Ten included studies were retrospective cohort and twenty-two were retrospective case series. The studies were conducted in the United States of America 5, 6, 8, 23, 25-39 , China [40][41][42] , Germany 24,43,44 , United Kingdom 22,45 , France 46,47 , Sweden 48 , Japan 49 and Taiwan 9 . A total of 10 851 patients with a mean age of 35-65 years received 12 769 free flaps (1.18 free flaps per patient) in reconstructive free tissue transfer procedures.…”