Micro additive manufacturing of glucose biosensors: A feasibility study

Nesaei, Sepehr; Yang, Song; Wang, Yijia; Ruan, Xiaofan; Du, Dan; Gozen, B. Arda; Lin, Yuehe

doi:10.1016/j.aca.2018.09.012

Cited by 66 publications

(29 citation statements)

References 35 publications

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“…Several add-ons and modications of the basic set-up described above can expand the versatility of the technique and the range of formulations used to increase the complexity of the printed object. For example by designing active mixers 43 and droplet generators; 47 attaching CCD cameras 48 or UV-light sources to cure polymers 49 (Fig. 2); using humidiers, suspension baths for embedded printing, and heated syringes and/or platforms; 50 combining DIW with additional Fused Deposition Modelling (FDM) printer heads 51 (Fig.…”

Section: Direct Ink Writing For Multi-materials Printingmentioning

confidence: 99%

Direct ink writing advances in multi-material structures for a sustainable future

et al. 2020

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Section: Direct Ink Writing For Multi-materials Printingmentioning

confidence: 99%

Direct ink writing advances in multi-material structures for a sustainable future

et al. 2020

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“…In addition to H 2 O 2 , glucose is another significant analyte that has been widely investigated by many researchers in the areas of diabetes monitoring, food industries, and so on [43,85]. The concentration of glucose in the human body is an indicator of blood sugar concentration [86]. High blood sugar concentration can lead to obesity and diabetes, while low blood sugar concentration may result in hypoglycemia or epilepsy.…”

Section: Non-enzyme Electrochemical Sensorsmentioning

confidence: 99%

Electrochemical Sensors Fabricated by Electrospinning Technology: An Overview

Chen

Chou

Liu

et al. 2019

Sensors

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Nanofibers or nanofibrous membranes prepared by electrospinning possess many attractive properties, including excellent mechanical properties, high specific surface area and high porosity, making them attractive for sensor application, especially for the electrochemical sensors. Many nanomaterials are used as additives to improve the conductivity, sensitivity and selectivity of sensors. Based on the different modifiers of electrode materials, electrochemical sensors can be divided into enzyme sensors and non-enzyme sensors. In this review, we summarize the recent progress of the electrochemical sensors fabricated by electrospinning, including hydrogen peroxide (H2O2) sensors, glucose sensors and other sensors. In addition, the sensing mechanisms of various electrochemical sensors are introduced in detail. Finally, future research directions of electrochemical sensors based on electrospinning and the challenges faced by large-scale applications of electrospun electrochemical sensors are presented.

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“…where E is the membrane potential, E 0 is the standard potential, R is the gas constant, T is the temperature in Kelvins, and F is the Faraday's constant. The sensing mechanism of the potentiometric glucose biosensor is expressed in the enzymatic reaction formulas (3,4)…”

Section: B Average Sensitivity and Linearity Of Mbs-nafion-gox/go/azmentioning

confidence: 99%

Integrating a Plastic Glucose Biosensor Based on Arrayed Screen-Printed Electrodes Utilizing Magnetic Beads with a Microfluidic Device

Chou

Lin

Kuo

et al. 2019

IEEE J. Electron Devices Soc.

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In this study, a novel potentiometric glucose biosensor based on magnetic beads-Nafionglucose oxidase/graphene oxide/aluminium-doped zinc oxide (MBs-Nafion-GOx/GO/AZO) membranes on a PET substrate with arrayed screen-printed electrodes (SPEs) was proposed. The morphologies, elemental analysis, and surface roughnesses of the sensing membranes were characterized. The sensing parameters of the biosensor were investigated by using the voltage-time (V-T) measurement system, which measured sensitivity, linearity, anti-interference ability, reversibility, temperature effect, and lifetime. A microfluidic device using polydimethylsiloxane (PDMS) was integrated with the V-T measurement system to analyze the response characteristics. The results under static solution and microfluidic flow conditions were compared. The results showed that the average sensitivity and linearity of the biosensor depended on the microfluidic flow rate. The best average sensitivity of the glucose biosensor based on MBs-Nafion-GOx/GO/AZO membranes was 20.35 mV/mM at a flow rate of 15 µL/min. INDEX TERMS Aluminium-doped zinc oxide (AZO), graphene oxide (GO), magnetic beads (MBs), glucose biosensor, screen-printed electrodes (SPEs), microfluidics.

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Micro additive manufacturing of glucose biosensors: A feasibility study

Cited by 66 publications

References 35 publications

Direct ink writing advances in multi-material structures for a sustainable future

Direct ink writing advances in multi-material structures for a sustainable future

Electrochemical Sensors Fabricated by Electrospinning Technology: An Overview

Integrating a Plastic Glucose Biosensor Based on Arrayed Screen-Printed Electrodes Utilizing Magnetic Beads with a Microfluidic Device

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