Micellar catalysis in the systems arylamine-diphenylamine-NO 2 −

Doronin, S. Yu.; Chernova, R. K.

doi:10.1134/s1070363208110066

Cited by 1 publication

(1 citation statement)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…of PTC up to 0.5 eq., there appears to be almost no visible increase in the conversion. It is known that the use of anionic surfactants as phase transfer catalysts to increase the rate of chemical reactions in two phase media not only utilize their ability to increase the interfacial area [23] between the two phases by lowering the interfacial surface tension but also through micellar catalysis [31]. The effect of the latter phenomena on the rate of a chemical reaction can be confirmed by the behavioral trend of the rate of the reaction around the critical micelle concentration (CMC) of the surfactant employed.…”

Section: Preparation Of Reactant Solutionsmentioning

confidence: 99%

A Facile Optimization of Diazotization and Phase Transfer Catalyzed Azo-Coupling Reactions in Microreactors

Akwi¹,

Bosma²,

Watts³

2016

J Flow Chem

View full text Add to dashboard Cite

Herein, we illustrate how microreactor technology can be used as a tool for reaction screening and optimization, in addition to improving the reaction chemistry. We report the in-situ generation of azo compounds by reactive quenching of diazonium intermediates in microreactors. This involves an electrophilic aromatic substitution reaction, namely, an azo-coupling reaction performed in continuous-flow systems in the presence of a phase transfer catalyst with great emphasis on compounds that do not easily couple. Capitalizing on the benefits of a large surface area and the short molecular diffusion distances observed in microreactors, in-situ phase transfer catalyzed azo-coupling reaction of diphenylamine to p-nitroaniline was investigated. A rapid and easy optimization protocol was established which yielded a 99%, 22%, and 33% conversion of diphenylamine, carbazole, and triphenylamine, respectively, in approximately 2.4 min.

show abstract

Section: Preparation Of Reactant Solutionsmentioning

confidence: 99%