MICAL1 stability by PlexinA1 promotes gastric cancer cell migration
fengwen ye,
Tianxiang Xia,
Yueyuan Wang
et al.
Abstract:Background
For metastasis to proceed, tumor cells must become mobile by modulating their cytoskeleton. MICAL1 is known as an actin cytoskeleton regulator, but the mechanisms by which it drives cancer cell migration are still unclear.
Methods
Immunohistochemistry assays and western blotting were used to detect the expression levels of MICAL1 in gastric cancer tissues and cells. Immunoprecipitation and immunofluorescence staining were used to detect the interactions of proteins. Wound-healing and transwell ass… Show more
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