MgNi2O3 nanoparticles as novel and versatile sensing material for non-enzymatic electrochemical sensing of glucose and conductometric determination of acetone

Lavanya, N.; Leonardi, Salvatore Gianluca; Marini, Silvia; Espro, Claudia; Kanagaraj, M.; Reddy, Sathish; Sekar, C.; Neri, G.

doi:10.1016/j.jallcom.2019.152787

Cited by 22 publications

(10 citation statements)

References 37 publications

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“…The Sm substitution into the cobalt-ferrite host structure offers a proper microstructure for H 2 sensing. Less conventional MOX nanomaterials were also synthesized and processed for their application in conductometric sensors [ 92 , 93 , 94 , 95 ]. For example, another interesting activity about the MOX nanoparticles materials is that related to evaluating the effect of the irradiation by gamma rays (γ-rays) on their sensing properties [ 96 , 97 ].…”

Section: An Overview On Mox Nanomaterials Used For Gas Sensingmentioning

confidence: 99%

Metal-Oxide Based Nanomaterials: Synthesis, Characterization and Their Applications in Electrical and Electrochemical Sensors

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Spadaro

Corsaro

et al. 2021

Sensors

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112

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Pure, mixed and doped metal oxides (MOX) have attracted great interest for the development of electrical and electrochemical sensors since they are cheaper, faster, easier to operate and capable of online analysis and real-time identification. This review focuses on highly sensitive chemoresistive type sensors based on doped-SnO2, RhO, ZnO-Ca, Smx-CoFe2−xO4 semiconductors used to detect toxic gases (H2, CO, NO2) and volatile organic compounds (VOCs) (e.g., acetone, ethanol) in monitoring of gaseous markers in the breath of patients with specific pathologies and for environmental pollution control. Interesting results about the monitoring of biochemical substances as dopamine, epinephrine, serotonin and glucose have been also reported using electrochemical sensors based on hybrid MOX nanocomposite modified glassy carbon and screen-printed carbon electrodes. The fundamental sensing mechanisms and commercial limitations of the MOX-based electrical and electrochemical sensors are discussed providing research directions to bridge the existing gap between new sensing concepts and real-world analytical applications.

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Section: An Overview On Mox Nanomaterials Used For Gas Sensingmentioning

confidence: 99%

Metal-Oxide Based Nanomaterials: Synthesis, Characterization and Their Applications in Electrical and Electrochemical Sensors

Fazio

Spadaro

Corsaro

et al. 2021

Sensors

Self Cite

112

View full text Add to dashboard Cite

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“…This setup enabled bypassing of the micro-extraction process required for phenol detection with a simple dilution procedure [121]. Conductometric sensors have also been used for the detection of biomolecules from human serum and urine samples, and pathogens from foods for biosecurity purposes [118,122,123]. [117].…”

Section: Conductometric Techniquementioning

confidence: 99%

Metal Nanoparticles for Electrochemical Sensing: Progress and Challenges in the Clinical Transition of Point-of-Care Testing

et al. 2020

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With the rise in public health awareness, research on point-of-care testing (POCT) has significantly advanced. Electrochemical biosensors (ECBs) are one of the most promising candidates for the future of POCT due to their quick and accurate response, ease of operation, and cost effectiveness. This review focuses on the use of metal nanoparticles (MNPs) for fabricating ECBs that has a potential to be used for POCT. The field has expanded remarkably from its initial enzymatic and immunosensor-based setups. This review provides a concise categorization of the ECBs to allow for a better understanding of the development process. The influence of structural aspects of MNPs in biocompatibility and effective sensor design has been explored. The advances in MNP-based ECBs for the detection of some of the most prominent cancer biomarkers (carcinoembryonic antigen (CEA), cancer antigen 125 (CA125), Herceptin-2 (HER2), etc.) and small biomolecules (glucose, dopamine, hydrogen peroxide, etc.) have been discussed in detail. Additionally, the novel coronavirus (2019-nCoV) ECBs have been briefly discussed. Beyond that, the limitations and challenges that ECBs face in clinical applications are examined and possible pathways for overcoming these limitations are discussed.

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“…Electrochemical sensors have been gaining attention in the breath analysis area due to their highly selective nature, low cost, miniaturizability, low power requirement, and biocompatibility [ 8 ]. Lavanya et al reported the utility of a Zn-MgNi 2 O 3 conductometric sensor, selective to acetone and with a 0.5 ppb limit of detection [ 102 ]. Zn-MgNi 2 O 3 was also found suitable for electrochemical detection of glucose.…”

Section: Sensing Methodologies For Breath Analysismentioning

confidence: 99%

Exhaled Breath Analysis for Diabetes Diagnosis and Monitoring: Relevance, Challenges and Possibilities

et al. 2021

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With the global population prevalence of diabetes surpassing 463 million cases in 2019 and diabetes leading to millions of deaths each year, there is a critical need for feasible, rapid, and non-invasive methodologies for continuous blood glucose monitoring in contrast to the current procedures that are either invasive, complicated, or expensive. Breath analysis is a viable methodology for non-invasive diabetes management owing to its potential for multiple disease diagnoses, the nominal requirement of sample processing, and immense sample accessibility; however, the development of functional commercial sensors is challenging due to the low concentration of volatile organic compounds (VOCs) present in exhaled breath and the confounding factors influencing the exhaled breath profile. Given the complexity of the topic and the skyrocketing spread of diabetes, a multifarious review of exhaled breath analysis for diabetes monitoring is essential to track the technological progress in the field and comprehend the obstacles in developing a breath analysis-based diabetes management system. In this review, we consolidate the relevance of exhaled breath analysis through a critical assessment of current technologies and recent advancements in sensing methods to address the shortcomings associated with blood glucose monitoring. We provide a detailed assessment of the intricacies involved in the development of non-invasive diabetes monitoring devices. In addition, we spotlight the need to consider breath biomarker clusters as opposed to standalone biomarkers for the clinical applicability of exhaled breath monitoring. We present potential VOC clusters suitable for diabetes management and highlight the recent buildout of breath sensing methodologies, focusing on novel sensing materials and transduction mechanisms. Finally, we portray a multifaceted comparison of exhaled breath analysis for diabetes monitoring and highlight remaining challenges on the path to realizing breath analysis as a non-invasive healthcare approach.

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MgNi2O3 nanoparticles as novel and versatile sensing material for non-enzymatic electrochemical sensing of glucose and conductometric determination of acetone

Cited by 22 publications

References 37 publications

Metal-Oxide Based Nanomaterials: Synthesis, Characterization and Their Applications in Electrical and Electrochemical Sensors

Metal-Oxide Based Nanomaterials: Synthesis, Characterization and Their Applications in Electrical and Electrochemical Sensors

Metal Nanoparticles for Electrochemical Sensing: Progress and Challenges in the Clinical Transition of Point-of-Care Testing

Exhaled Breath Analysis for Diabetes Diagnosis and Monitoring: Relevance, Challenges and Possibilities

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