Metronomic Chemotherapy for Pediatric Refractory Solid Tumors: A Retrospective Single-Center Study
Yukari Sakurai,
Fuminori Iwasaki,
Ayana Hirose
et al.
Abstract:Metronomic chemotherapy (MC) is based on chronic administration of chemotherapeutic agents at minimally toxic doses without prolonged drug-free breaks, that inhibits tumor angiogenesis and induces tumor dormancy. This study aimed to determine the efficacy of MC for pediatric refractory solid tumors. We retrospectively analyzed the data of pediatric patients with relapsed/refractory solid tumors who received treatment, including low-dose continuous administration of anticancer drugs, at our institute. Of the 18… Show more
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