Metodología para el diseño computacional de andamios a ser utilizados en reparación ósea

Reboledo-Grau, Diana; Martínez, Gabriela

doi:10.18273/revuin.v19n4-2020025

Cited by 4 publications

(2 citation statements)

References 24 publications

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“…By refining materials and designs, the goal is to promote enhanced bone growth while mitigating the risk of rejection or associated complications from implanted devices [33]. Finite element modeling tailored to bone tissue dynamics plays a crucial role in iteratively designing and optimizing implants [34,35]. This approach enables thorough evaluations across critical parameters like load distribution and mechanical response, aiding in preemptively addressing potential complications such as fractures or implant loosening.…”

Section: Introductionmentioning

confidence: 99%

Characterization of Pig Vertebrae under Axial Compression Integrating Radiomic Techniques and Finite Element Analysis

Hernández-Salazar,

Chamorro,

González-Estrada

2024

Inventions

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The study of pig bones, due to their similarity with human tissues, has facilitated the development of technological tools that help in the diagnosis of diseases and injuries affecting the skeletal system. Radiomic techniques involving medical image segmentation, along with finite element analysis, enable the detailed study of bone damage, loss of density, and mechanical functionality, which is a significant advancement in personalized medicine. This study involves conducting experimental tests on L3–L6 pig vertebrae under axial loading conditions. The mechanical properties of these vertebrae are analyzed, and the maximum loads they can sustain within the elastic range are determined. Additionally, three-dimensional models are generated by segmenting computerized axial tomography (CAT) scans of the vertebrae. Digital shadows of the vertebrae are constructed by assigning an anisotropic material model to the segmented geometries. Then, finite element analysis is performed to evaluate the elastic characteristics, stress, and displacement. The findings from the experimental data are then compared to the numerical model, revealing a strong correlation with differences of less than 0.8% in elastic modulus and 1.53% in displacement. The proposed methodology offers valuable support in achieving more accurate medical outcomes, employing models that serve as a diagnostic reference. Moreover, accurate bone modeling using finite element analysis provides valuable information to understand how implants interact with the surrounding bone tissue. This information is useful in guiding the design and optimization of implants, enabling the creation of safer, more durable, and biocompatible medical devices that promote optimal osseointegration and healing in the patient.

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Section: Introductionmentioning

confidence: 99%

Characterization of Pig Vertebrae under Axial Compression Integrating Radiomic Techniques and Finite Element Analysis

Hernández-Salazar,

Chamorro,

González-Estrada

2024

Inventions

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“…During the last decades, much research has been carried out regarding structural capacity [8] , biocompatibility, cell growth speed [9] , shape and manufacturing process [10] , among others. These investigations have generated extensive and interesting information that has made it possible to make considerable improvements in this discipline.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Parameters in PLA and PCL Scaffolds to be Used in Cartilaginous Tissues

Rea¹

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The scopes of medical treatments involving organ transplants and implants for chronic problems and trauma have changed significantly. However, these procedures are subject to multiple problems. Recently, tissue engineering has been used to address them. The present study is framed in the field of tissue engineering, particularly cartilage tissue, and proposes the evaluation of geometric and impression parameters for the manufacture of scaffolds as a basis for the growth of cells through 3D impression techniques. These scaffolds are highly porous three-dimensional supports that house donated or himself patient cells, providing a surface where the cells can adhere and proliferate. In the methodology, geometric and pore size variables are defined for scaffolding modeling by using CAD techniques and standardization of the printing process with standard 3D printers and accessible materials. The results showed that material flow, printing temperature, printing speed and ventilation are the most influential parameters in the manufacture of scaffolds. Additionally, it was found micrometric variations between the modeled design and the printing result. These scaffolds will subsequently be subjected to in vitro cell culture evaluating the adherence, division, and proliferation of the cells.

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Characterization of hydroxyapatite coatings produced by pulsed-laser deposition on additive manufacturing Ti6Al4V ELI

2022

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Metodología para el diseño computacional de andamios a ser utilizados en reparación ósea

Cited by 4 publications

References 24 publications

Characterization of Pig Vertebrae under Axial Compression Integrating Radiomic Techniques and Finite Element Analysis

Characterization of Pig Vertebrae under Axial Compression Integrating Radiomic Techniques and Finite Element Analysis

Evaluation of Parameters in PLA and PCL Scaffolds to be Used in Cartilaginous Tissues

Characterization of hydroxyapatite coatings produced by pulsed-laser deposition on additive manufacturing Ti6Al4V ELI

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