Methylsulfonyl Zn phthalocyanine: A polyvalent and powerful hydrophobic photosensitizer with a wide spectrum of photodynamic applications

İşçi, Ümit; Beyreis, Marlena; Tortik, Nicole; Topal, Sevinç Zehra; Glueck, Michael; Ahsen, Vefa; Dumoulin, Fabienne; Kiesslich, Tobias; Plaetzer, Kristjan

doi:10.1016/j.pdpdt.2015.10.010

Cited by 27 publications

(8 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The development of alternative antimicrobial treatment modalities comes with the development of new classes of antimicrobials like metal complexes [ 7 , 8 , 9 ]. Among them, Ru(II) complexes, including Ru(II) polypyridyl complexes, hold great promise to inactivate and eradicate pathogenic microorganisms including bacteria, fungi, and viruses [ 10 , 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Encapsulation of a Ru(II) Polypyridyl Complex into Polylactide Nanoparticles for Antimicrobial Photodynamic Therapy

et al. 2020

View full text Add to dashboard Cite

Antimicrobial photodynamic therapy (aPDT) also known as photodynamic inactivation (PDI) is a promising strategy to eradicate pathogenic microorganisms such as Gram-positive and Gram-negative bacteria. This therapy relies on the use of a molecule called photosensitizer capable of generating, from molecular oxygen, reactive oxygen species including singlet oxygen under light irradiation to induce bacteria inactivation. Ru(II) polypyridyl complexes can be considered as potential photosensitizers for aPDT/PDI. However, to allow efficient treatment, they must be able to penetrate bacteria. This can be promoted by using nanoparticles. In this work, ruthenium-polylactide (RuPLA) nanoconjugates with different tacticities and molecular weights were prepared from a Ru(II) polypyridyl complex, RuOH. Narrowly-dispersed nanoparticles with high ruthenium loadings (up to 53%) and an intensity-average diameter < 300 nm were obtained by nanoprecipitation, as characterized by dynamic light scattering (DLS). Their phototoxicity effect was evaluated on four bacterial strains (Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Pseudomonas aeruginosa) and compared to the parent compound RuOH. RuOH and the nanoparticles were found to be non-active towards Gram-negative bacterial strains. However, depending on the tacticity and molecular weight of the RuPLA nanoconjugates, differences in photobactericidal activity on Gram-positive bacterial strains have been evidenced whereas RuOH remained non active.

show abstract

Section: Introductionmentioning

confidence: 99%

Encapsulation of a Ru(II) Polypyridyl Complex into Polylactide Nanoparticles for Antimicrobial Photodynamic Therapy

et al. 2020

View full text Add to dashboard Cite

show abstract

“…The shoulders observed inside of the reflectance spectrum indicate that the TiO 2 /sensitizer thin films are optically active in the visible region of electromagnetic spectrum; in the sensitization process, the sensitizer alters the semiconductor by two ways: (a) energy transfer and (b) electronic [29]; Figure 3 shows typical signals for phycocyanins (phycocyanin-C and allophycocyanin), with a maximum spectral profile of 615, 340, and 260 and shoulders at 650 and 400 nm. These results agree with other reports;…”

Section: Tio 2 /Sensitized Thin Film Optical Characterizationmentioning

confidence: 99%

Cyanobacterial Biomass Pigments as Natural Sensitizer for TiO₂ Thin Films

Patiño-Camelo

Díaz‐Uribe

Gallego-Cartagena

et al. 2019

International Journal of Photoenergy

View full text Add to dashboard Cite

In this work, we studied the effect of TiO2 sensitization with dry biomass extracted of cyanobacteria on the degradation of methylene blue dye (AM). Cyanobacterial cultures isolated from water samples were collected from the swamp of Malambo in Colombia; two main genera of cyanobacteria were identified, and they were cultivated with BG-11 culture medium. The concentrations of chlorophyll a in the exponential and stationary phases of growth were measured; the phycobilin content was quantified by spectrophotometry. Thin films of TiO2 were deposited by a doctor blade method, and they were sensitized by wet impregnation. Furthermore, a methylene blue (MB) photodegradation process was studied under visible light irradiation on the cyanobacterial biomass sensitized TiO2 material (TiO2/sensitizer); besides, the pseudo-first-order model was used to obtain kinetic information about photocatalytic degradation. The results showed that the BG-11+ treatment reported a higher amount of dry biomass and phycobiliproteins. After the sensitization process, the TiO2/sensitizer thin films showed a significant red shift in the optical activity; besides the thin film roughness decreasing, the TiO2/sensitizer showed photocatalytic activity of 23.2% under visible irradiation, and besides, the kinetic (kap) constant for TiO2/sensitizer thin films was 3.1 times greater than the kap value of TiO2 thin films. Finally, results indicated that cyanobacterial biomass is a suitable source of natural sensitizers to be used in semiconductor sensitization.

show abstract

“…Titanium dioxide is photocatalytic active under UV radiation and sensitization improves the TiO 2 photoactivity in visible range of electromagnetic spectrum. In sensitization process, a molecular entity (sensitizer) alters other molecule (semiconductor) by energy transfer or electronic transfer from sensitizer to semiconductor after radiation absorption [36]. In this process, phthalocyanine absorbs the visible light, after that, it is excited to a state of greater energy leaving an electron in the lowest energy unoccupied molecular orbital (LUMO) orbital.…”

Section: Sensitization Processmentioning

confidence: 99%

Phthalocyanines: Alternative Sensitizers of TiO2 to be Used in Photocatalysis

Vallejo¹,

Díaz‐Uribe²,

Quiñones³

et al. 2017

Phthalocyanines and Some Current Applications

View full text Add to dashboard Cite

Currently, titanium dioxide is a most researched semiconductor in photocatalysis field; however, practical applications of TiO 2 are limited due to high band gap (3.2 eV). In last decades, researchers implemented several strategies to improve photoactivity of TiO 2 in visible electromagnetic spectrum. Titanium dioxide (TiO 2) sensitization for absorption of naturals and/or synthetics organic dyes is an important research subject in the field, and it is an efficient method to develop practical application in waste treatment. In this chapter, we review main theoretical aspects of sensitization process of TiO 2 by phthalocyanines and its effect in photocatalytic properties. In the last section, we review reports of photocatalytic systems.

show abstract

Methylsulfonyl Zn phthalocyanine: A polyvalent and powerful hydrophobic photosensitizer with a wide spectrum of photodynamic applications

Cited by 27 publications

References 30 publications

Encapsulation of a Ru(II) Polypyridyl Complex into Polylactide Nanoparticles for Antimicrobial Photodynamic Therapy

Encapsulation of a Ru(II) Polypyridyl Complex into Polylactide Nanoparticles for Antimicrobial Photodynamic Therapy

Cyanobacterial Biomass Pigments as Natural Sensitizer for TiO₂ Thin Films

Phthalocyanines: Alternative Sensitizers of TiO2 to be Used in Photocatalysis

Contact Info

Product

Resources

About

Methylsulfonyl Zn phthalocyanine: A polyvalent and powerful hydrophobic photosensitizer with a wide spectrum of photodynamic applications

Cited by 27 publications

References 30 publications

Encapsulation of a Ru(II) Polypyridyl Complex into Polylactide Nanoparticles for Antimicrobial Photodynamic Therapy

Encapsulation of a Ru(II) Polypyridyl Complex into Polylactide Nanoparticles for Antimicrobial Photodynamic Therapy

Cyanobacterial Biomass Pigments as Natural Sensitizer for TiO2 Thin Films

Phthalocyanines: Alternative Sensitizers of TiO2 to be Used in Photocatalysis

Contact Info

Product

Resources

About

Cyanobacterial Biomass Pigments as Natural Sensitizer for TiO₂ Thin Films