Methylmalonic aciduria and homocystinuria-associated maculopathy

Abstract

exists about its metabolism and effects on development. 3 Given the rarity of its use in children, performing a randomised control trial is unrealistic, but an alternative method would be to establish a central database that allows clinicians who use anti-vascular endothelial growth factor therapy in children to report results and complications. Conflict of interestThe authors declare no conflict of interest. References

A woman with bilateral maculopathy and acquired vitamin B12 deficiency

“…The fundus appearance and fluorescein angiogram findings were similar to those described in cases of congenital MMA. 4,5 Full-field electroretinograms revealed mildly reduced scotopic and photopic responses in the left eye.…”