Methylation of the thiophene ring using Carbon‐11‐labelled methyl iodide: formation of 3‐[<sup>11</sup>C]methylthiophene

Karramkam, Mylène; Demphel, Stéphane; Hinnen, Françoise; Trognon, C.; Dollé, Frédéric

doi:10.1002/jlcr.665

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Carbon ( 11 C)1

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2004

2021

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Cited by 6 publications

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“…[ 11 C]methyl iodide is, of course, one of the most widely used reagents for labelling radiopharmaceuticals with carbon-11. Labelled methyl derivatives of estradiol, 92 proteinases, 93 thymine, 94 thiazols 95 and thiophene 96 have been prepared from [ 11 C]CH 3 I as well as labelled carfentanil, 97 vorozole, 98 zolpidem 99 and methylmetaraminol. 100 Even more complex biomolecules which are best referred to in code such as NS2495, 101 FK-506, 102 DAA1106, 103 NPS1506 104 or Ro15-4513 105 have all been labelled efficiently and quickly using [ 11 C]methyl iodide.…”

Section: Carbon ( 11 C)mentioning

confidence: 99%