Methyl ?-phenylacetate in the Fischer indole synthesis

Shvedov, V. I.; Kurilo, G. N.; Grinev, A. N.

doi:10.1007/bf00476326

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5 Synthesis Of 5h-benzo[b]carbazole-611-diones From 2-aminom...2

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“…Scheme 205). 425 426,427 However, this method failed using electron-deficient olefins or N-substituted-1,4-naphthoquinones. 428 431…”

Section: Synthesis Of 5h-benzo[b]carbazole-611-diones From 2-aminomet...mentioning

confidence: 99%

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Isolation and Synthesis of Biologically Active Carbazole Alkaloids

2002

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“…Scheme 205). 425 426,427 However, this method failed using electron-deficient olefins or N-substituted-1,4-naphthoquinones. 428 431…”

Section: Synthesis Of 5h-benzo[b]carbazole-611-diones From 2-aminomet...mentioning

confidence: 99%

“…The key steps of this approach were a Fischer indolization of the N -methyl- N -phenylhydrazone of methyl γ-phenylacetoacetate and a subsequent polyphosphoric acid-promoted cyclization (cf. Scheme ) …”

Section: 5 Synthesis Of 5h-benzo[b]carbazole-611-diones From 2-aminom...mentioning

confidence: 99%

Isolation and Synthesis of Biologically Active Carbazole Alkaloids

2002

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Arbidol: a quarter-century after. Past, present and future of the original Russian antiviral

Balakin¹,

Filosa²,

Лавренов³

et al. 2018

Russ. Chem. Rev.

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The present review is concerned with the synthesis and structure–activity relationship studies of Arbidol and its structural analogues. The latter are roughly divided into several unequal parts: indole- and benzofuran-based compounds, benzimidazole and imidazopyridine bioisosteres and ring-expanded quinoline derivatives. Much attention is focused on various types of antiviral activity of the above-mentioned Arbidol congeners, as well as of the parent compound itself. Features of Arbidol synthesis and metabolic changes are also discussed. The bibliography includes 166 references.

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Methyl ?-phenylacetate in the Fischer indole synthesis

Cited by 2 publications

References 4 publications

Isolation and Synthesis of Biologically Active Carbazole Alkaloids

Isolation and Synthesis of Biologically Active Carbazole Alkaloids

Arbidol: a quarter-century after. Past, present and future of the original Russian antiviral

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