Methotrexate plus narrowband UVB phototherapy versus narrowband UVB phototherapy alone in the treatment of plaque-type psoriasis: A randomized, placebo-controlled study

Phototherapy and Photochemotherapy for Psoriasis

“…Methotrexate was started 3 weeks before the start of phototherapy, in a dose of 15 mg/week. 44 The combination of methotrexate with PUVA is not recommended because of an increased risk of skin cancer.…”

Cutaneous T-cell lymphoma in skin of color

“…Three of the more traditional choices at this point are interferon therapy, 47 retinoid therapy, 48 and methotrexate therapy. 51,52 All three have been shown to enhance a response to phototherapy and are discussed later in systemic therapies commonly used in managing MF in skin of color. Interferon-alfa is dosed from 3 to 18 M units subcutaneously three times per week, methotrexate is typically given in weekly doses ranging from 15 to 30 mg per week, and the retinoid bexarotene is used at doses of 150 to 450 mg per day in conjunction with phototherapy to achieve remission.…”

Current Approach to Phototherapy Applications in Dermatology Practice: Part 2. Phototherapy in Vitiligo, Mycosis Fungoides, Atopic Dermatitis, Sclerosing Diseases and Psoriasis

“…Dar bant UVB ile metotreksat kombinasyonunun da, tek başına dar bant UVB'ye göre yanıt oranını artırdığı ve yanıt için gerekli seans sayısını azalttığı gösterilmiştir (95,96). 2010 yılında yapılan bir çalışmada, dar bant UVB ve metotreksat kombinasyonu ile hastaların %95'inde, tek başına dar bant UVB ile ise hastaların %70'inde PAŞİ 75 yanıtı elde edilmiştir (96).…”