Methotrexate and cardiovascular prevention: an appraisal of the current evidence
Arduino A. Mangoni,
Salvatore Sotgia,
Angelo Zinellu
et al.
Abstract:New evidence continues to accumulate regarding a significant association between excessive inflammation and dysregulated immunity (local and systemic) and the risk of cardiovascular events in different patient cohorts. Whilst research has sought to identify novel atheroprotective therapies targeting inflammation and immunity, several marketed drugs for rheumatological conditions may serve a similar purpose. One such drug, methotrexate, has been used since 1948 for treating cancer and, more recently, for a wide… Show more
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