Methods of Treatment of Anemia associated with Antitumor Cytostatic Therapy in Cancer Patients in Real Clinical Practice, Based on the Results of a Retrospective Analysis

Yessentayeva, Suriya; Kaibullayev, Berik A.; Nurzhanov, Abay K.; Zhakenova, Zhanar; Sarsenbayeava, Galiya E.; Turasheva, Gulzhan B.; Ilyanova, Zarina T.

doi:10.5958/0974-360x.2018.00702.3

Rese. Jour. of Pharm. and Technol.

2018

DOI: 10.5958/0974-360x.2018.00702.3

|View full text |Cite

Methods of Treatment of Anemia associated with Antitumor Cytostatic Therapy in Cancer Patients in Real Clinical Practice, Based on the Results of a Retrospective Analysis

Suriya Yessentayeva¹,

Berik A. Kaibullayev²,

Abay K. Nurzhanov³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2022

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

2-Pyrocatechuic Acid Attenuates Carboplatin Induced Hematological Toxicities in Wistar Rats

Pujari

Bandawane²

2022

RJPT

View full text Add to dashboard Cite

Hematological toxicity or pancytopenia produced by carboplatin chemotherapy tends to limit the clinical usage of carboplatin as a potent antineoplastic agent. The current investigation was aimed at evaluation of the protective activity of a plant phenolic acid i.e. 2-pyrocatechuic acid (2,3 dihyroxybenzoic acid) against hematological adverse effects induced by carboplatin in Wistar rats. Intraperitoneal injection carboplatin (35 mg/kg) for 6 days resulted in significant alterations in hematological parameters such as decreased red blood cell, hemoglobin, total leukocyte and differential leukocyte counts and increased eosinophil counts in rat blood indicating severe hematological toxicities. Pre and co-administration of 2-pyrocatechuic acid at the doses 10, 30 and 100 with CP significantly attenuated the altered hematological indices in a dose-dependent manner exhibiting its efficacy as a protective agent for the amelioration and prevention of hematological toxicities induced by carboplatin chemotherapy.

show abstract

2-Pyrocatechuic Acid Attenuates Carboplatin Induced Hematological Toxicities in Wistar Rats

Pujari

Bandawane²

2022

RJPT

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Methods of Treatment of Anemia associated with Antitumor Cytostatic Therapy in Cancer Patients in Real Clinical Practice, Based on the Results of a Retrospective Analysis

Cited by 1 publication

References 0 publications

2-Pyrocatechuic Acid Attenuates Carboplatin Induced Hematological Toxicities in Wistar Rats

2-Pyrocatechuic Acid Attenuates Carboplatin Induced Hematological Toxicities in Wistar Rats

Contact Info

Product

Resources

About