Methods of encapsulation efficiency determination

Abstract

In this article selected methods of encapsulation efficiency determination are presented. Five analytical methods were compared: (i) with the use of the gas chromatography coupled with mass detector, (ii) by staining oil with rhodamine B, (iii) using Raman spectroscopy (iv) spectrophotometry with and without the addition of a contrasting substance, (v) by analyzing DSC thermograms normalized for oil and powders containing this oil. In order to compare the above-mentioned methods, spray drying microencapsulation experiment was carried out. The results of the comparison allow to determine the accuracy as well as strengths and weaknesses of each of the proposed methods for determining the efficiency of microencapsulation in spray drying.