Methods for the synthesis of vinyl sulfides

Alkyne Hydrothiolation Catalyzed by a Dichlorobis(aminophosphine) Complex of Palladium: Selective Formation of cis‐Configured Vinyl Thioethers

“…Furthermore, sulfur-containing organic compounds commonly exhibit biological activity, and hence are frequently found in naturally occuring compounds. Moreover, these compounds have found applications in materials science, [1][2][3][4][5] and thus are valuable synthetic targets. The increasing demand for vinyl thioethers expedited the development of new synthetic methods for these target compounds.…”

Metal‐Free I2‐Catalyzed Sulfenylation of Dihydropyrans: Synthesis of Vinyl Sulfides

“…Therefore, they are valuable synthetic targets and a number of procedures for their preparation have been developed. The methods used for the synthesis of vinyl sulfides can be divided into two main groups: electrophilic sulfenylation of unsaturated compounds and nucleophilic thiolation of alkynes . There are, of course, other methods for the synthesis of vinyl sulfides, which can be illustrated by only a few examples, such as cross‐coupling of vinyl halides with thiols, addition of hydrogen halides to alkynyl sulfides, addition of thiols to ketones, α,β ‐elimination of thiols from dithioacetals and dithioketals, reduction of sulfoxides with subsequent α,β ‐elimination, Wittig‐Horner and Peterson reactions …”

In Quest of “Stereoselective Switch” for On-Water Hydrothiolation of Terminal Alkynes Using Different Additives and Green Synthesis of Vicinal Dithioethers

“…Organosulfur compounds play a key role in biological processes, new materials, and chemical synthesis [1,2]. 1-Alkenyl sulfides are important synthetic intermediates in total synthesis of many naturally occurring and biologically active compounds as well as versatile building blocks for many functionalized molecules [3][4][5][6][7][8][9]. The synthetic utility of alkenyl sulfides has been demonstrated in several reports by different research groups [10][11][12][13][14][15][16][17].…”