Methods for Retrospective Detection of Exposure to Toxic Scheduled Chemicals. Part B: Mass Spectrometric and Immunochemical Analysis of Covalent Adducts to Proteins and DNA
Abstract:In this article, an overview is presented of the methods that are currently available for retrospective detection of exposure to a number of chemical warfare agents (CWAs), based on adducts formed with macromolecules such as proteins. These methods can be applied for various purposes, e.g. diagnosis and dosimetry of exposure of casualties, confirmation of nonexposure, and verification of nonadherence to the Chemical Weapons Convention, health surveillance, and forensic purposes. The advantage of using protein … Show more
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