Methods and application areas of endoscopic optical coherence tomography

Yaqoob, Zahid; Wu, Jigang; McDowell, Emily J.; Heng, Xin; Yang, Changhuei

doi:10.1117/1.2400214

Cited by 121 publications

(90 citation statements)

References 196 publications

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“…Thus, it is a useful tool for observing neoplasm spread across the transbronchial mucosa, and is the top ranking method for early diagnosis of lung cancer [7,8]. In this study, we developed an OCT probe that employs a scanning ber endoscope (with a diameter of 1 mm) and an electromagnetic mechanism [6].…”

Section: Introductionmentioning

confidence: 99%

Forward-looking OCT Probe Using Single-fiber Scanning for Transbronchial Puncturing Cytodiagnosis

Matsunaga

Suda

et al. 2017

ABE

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Bronchoscopic diagnosis of peripheral lung cancer with ground-glass opacity (GGO) is dif cult because GGO lesions cannot be visualized using currently available radial probe endobronchial ultrasound. Therefore, a forward-looking single ber scanning optical coherence tomography (OCT) probe with a local observation function has been developed to achieve precise sampling. The new OCT probe is only 1 mm in diameter. The probe is composed of a patterned electroplated copper coil fabricated on a polyimide tube using non-planar photofabrication technique, and an optical ber having a permanent magnetic tube with a diameter of 0.5 mm. When an electrical alternating current is supplied to the coil, the permanent magnet vibrates electromagnetically with the optical ber. To increase the ber vibration amplitude, a micro gradient-index (GRIN) lens is set in front of the tip of the optical ber. Using the micro GRIN lens, the output beam is focused, and the scanning range is enlarged. The view angle becomes approximately 45 , and image resolution becomes approximately 60 μm. The structure of grating was successfully imaged using the new OCT probe. Further improvements and animal experiments are necessary to determine the clinical application of the probe.

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Section: Introductionmentioning

confidence: 99%

Forward-looking OCT Probe Using Single-fiber Scanning for Transbronchial Puncturing Cytodiagnosis

Matsunaga

Suda

et al. 2017

ABE

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“…OCT systems based on fiber-optic endoscopic and handheld probes [19][20][21] have been developed for preclinical and clinical researches. They have the advantages of compactness, flexibility, alignment free, high-speed scanning, and particularly good compatibility with other fiber-based systems.…”

Section: Introductionmentioning

confidence: 99%

Single-step method for fiber-optic probe-based full-range spectral domain optical coherence tomography

et al. 2013

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We propose a single-step method appropriated for a fiber-optic probe-based full-range spectral domain optical coherence tomography (OCT). The fiber-optic probe was scanned over a sample with a magnetically driven actuator. In the reference arm, a phase shift of π∕2 was applied during two neighbor axial scanning, from which the complex spectral interferogram was directly reconstructed. Since the complexconjugate-free OCT image is obtained by doing just one Fourier transform on the complex interferogram, obtaining the full-range image is simple in algorithm and effective in computation time. Some full-range images of biological samples created with the proposed method are presented and the processing time is analyzed.

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“…Cardiovascular imaging [20][21][22][23][24][25][26][27] has become the next big thing when the coronary OCT products have seen FDA clearance in the United States. Besides the two types of applications, OCT holds promise in dermatological 8,[28][29][30][31] , dental [32][33][34][35][36][37][38][39][40][41][42][43] , small animal [44][45][46] , development biology [47][48][49] , and various endoscopic applications [50][51][52][53][54][55] such as for esophagus, colon, and ovarian imaging.…”

Section: Introductionmentioning

confidence: 99%