Methodology Considerations in Studying Mental Health, Sleep Quality, and Biopsychosocial Determinants Among Chinese and Korean Americans During the COVID-19 Pandemic

Bai, Jinbing; Zhang, Wenhui; Choi, Dae-Sung; Kim, Sangmi

doi:10.2196/39760

Cited by 2 publications

(1 citation statement)

References 47 publications

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“…All eligible participants provided verbal consent to be included in this study. Following the consent, the study team emailed participants the REDCap online survey link where they completed the online surveys and provided their contact information (name, mailing address, phone number, and email address) for shipping the microbiome data collection kits, which included pictorial and written instructions in English, Chinese, or Korean (Bai et al, 2022). Our research staff also sent weekly reminders prompting participants to return their stool samples to our laboratory.…”

Section: Study Proceduresmentioning

confidence: 99%

A Pilot Study of the Gut Microbiota Associated With Depressive Symptoms and Sleep Disturbance Among Chinese and Korean Immigrants in the United States

Hope

Shen

Zhang

et al. 2022

Biological Research For Nursing

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Context Depression is prevalent among Asian Americans (AsA) during the COVID-19 pandemic, and depression often leads to sleep disturbance in this population. The gut microbiota (GM) plays a critical role in mental health and sleep quality, and the composition of the GM is largely unknown among AsA. Objectives Examine associations of the GM with depressive symptoms and sleep disturbance among Chinese and Korean American immigrants. Methods Depressive symptoms (PROMIS Short Form-Depression) and sleep quality (Pittsburgh Sleep Quality Index [PSQI]) were collected via surveys. PROMIS measure T-score > 55 indicates positive depressive symptoms, and a total PSQI score > 5 indicates sleep disturbance. 16S rRNA V3-V4 gene regions were sequenced from fecal specimens to measure GM. Permutational multivariate analysis of variance and linear discriminant analysis effect size were applied to examine associations of the GM with symptoms. Results Among 20 participants, 55% ( n = 11) reported depressive symptoms and 35% ( n = 7) reported sleep disturbance. A higher α-diversity was marginally associated with lower depressive symptoms: Chao1 (r = −0.39, p = 0.09) and Shannon index (r = −0.41, p = 0.08); β-diversity distinguished participants between categories of depressive symptoms (weighted UniFrac, p=0.04) or sleep disturbance (Jaccard, p=0.05). Those with depressive symptoms showed a higher abundance of Actinobacteria, while those without depressive symptoms had a higher abundance of Bacteroidetes. No significant taxa were identified for sleep disturbance. Conclusions Gut microbial diversity showed promising associations with depressive symptoms and sleep disturbance among Chinese and Korean immigrants. Specific taxa were identified as associated with depressive symptoms. Future studies with a larger sample size are warranted to confirm our findings.

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Section: Study Proceduresmentioning

confidence: 99%

A Pilot Study of the Gut Microbiota Associated With Depressive Symptoms and Sleep Disturbance Among Chinese and Korean Immigrants in the United States

Hope

Shen

Zhang

et al. 2022

Biological Research For Nursing

View full text Add to dashboard Cite

show abstract

Oral Microbiome, Mental Health, and Sleep Outcomes During the COVID-19 Pandemic: An Observational Study in Chinese and Korean American Immigrants

Richardson

Noh

Webster

et al. 2023

OMICS: A Journal of Integrative Biology

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Methodology Considerations in Studying Mental Health, Sleep Quality, and Biopsychosocial Determinants Among Chinese and Korean Americans During the COVID-19 Pandemic

Abstract: International Registered Report Identifier (IRRID) RR2-10.1136/bmjopen-2020-047281

Cited by 2 publications

References 47 publications

A Pilot Study of the Gut Microbiota Associated With Depressive Symptoms and Sleep Disturbance Among Chinese and Korean Immigrants in the United States

A Pilot Study of the Gut Microbiota Associated With Depressive Symptoms and Sleep Disturbance Among Chinese and Korean Immigrants in the United States

Oral Microbiome, Mental Health, and Sleep Outcomes During the COVID-19 Pandemic: An Observational Study in Chinese and Korean American Immigrants

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