Methodological Issues and Research Recommendations for Prognosis After Mild Traumatic Brain Injury: Results of the International Collaboration on Mild Traumatic Brain Injury Prognosis

Long-term health outcomes after exposure to repeated concussion in elite level: rugby union players

“…Finally, although detectable but ‘non-clinical’ differences were found on some cognitive measures between the groups, the reason for this is uncertain. Although brain pathology could be the cause, these differences could reflect psychological attributions about mTBI and the impact of retrospective recall bias on symptom reporting 12 43 44. The latter interpretation may even seem more plausible given the absence of significant relationships between scores on cognitive or mental health measures and the high number of repeat mTBI in RIRP.…”

Risk of suicide after a concussion

“…95 Long-term predictions and generalizability are also problematic because of the network of intervening factors and shifting definitions of concussion. 47,96,97 Some patients with concussion receive care that may mitigate the risk of suicide, such as antidepressant medication; 98,99 however, our study lacked data on such care, which remains a topic for future research.…”

“…[43][44][45] Patients who were admitted to hospital immediately or within 2 days of injury were excluded because such cases tend to reflect severe brain injury (a known risk factor for suicide) and do not represent ambulatory patients with concussion. 46,47 Patients under 17 years of age were excluded because most suicide deaths occur in adults. 48,49 Otherwise, the selection criteria were fully comprehensive and included all patients seeking care whose diagnosis was made by a physician.…”

Diagnostic performance of S100B protein serum measurement in detecting intracranial injury in children with mild head trauma

“…This condition accounts in the USA for more than 500 000 visits a year in children 1. The vast majority of children with mild TBI, defined as GCS 13–15,2 have no intracranial injury (ICI):3 a lesion is seen in 3–7% of these children undergoing CT3–6 and only 0.1–0.6% need a neurosurgical intervention 3 5…”