Methodological challenges in the evidence synthesis of health outcomes of digital health technologies
Hossein Motahari Nezhad
Abstract:Medical devices and pharmaceuticals are worlds apart, but healthcare would be impossible without them. Digital biomarkers are the subject of this thesis defined as objective, measurable, physiological, and behavioural parameters collected using wearable, portable, implantable, or digestible digital devices. Since the 1970s, systematic reviews and meta-analyses have dominated medical evidence synthesis. They provide medical decision-making evidence. To avoid biases and maintain methodological quality, the Cochr… Show more
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