In this paper, we present the design, development, implementation and evaluation of a virtual learning environment that supports the learning process of long term sick children. We envision a solution that helps to establish high quality involvement of the long term sick children in a communication-based scenario between the place where the child stays/has been moved and the original classroom/school setting. Analysis of existing ICT-based solutions reveals weaknesses such as the exclusive focus on instruction (and absence of social involvement), the high cost of developing, and mobility issues. Our system, however, is based on concrete user needs, is educationally and socially sound and relevant, and offers a scalable and affordable solution. To this end we incorporate innovative hardware, software and connectivity features, set in a user friendly user interface based on 3D technologies.