Methodological approaches for the assessment of bisphenol A exposure

Costa, Sofia; Severo, Mílton; Correia, Daniela; Carvalho, Catarina; Magalhães, Vânia; Vilela, Sofia; Cunha, Sara C.; Casal, Susana; Lopes, Carla; Torres, Duarte

doi:10.1016/j.foodres.2023.113251

Cited by 3 publications

(1 citation statement)

References 53 publications

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“…Similarly, the daily intake of BPA for Turkish women was 170 ng/kg bw/day based on 24-h dietary review data [ 10 ], while in Taiwan, China, the daily intake of BPA for children was 201 ng/kg bw/day [ 11 ]. The BPA intake for the Portuguese population was between these two values, with adolescents and adults having a daily intake of 79.1 and 46.1 ng/kg bw/day, respectively [ 12 ]. In addition, the concentrations of BPA, BPF, and BPS in water are 0.0095–0.173 μg/L, 0.0024–0.282 μg/L and 0.0016–0.0598 μg/L, respectively [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Invisible Hand behind Female Reproductive Disorders: Bisphenols, Recent Evidence and Future Perspectives

Wu,

Tian,

Zhu

et al. 2023

Toxics

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Reproductive disorders are considered a global health problem influenced by physiological, genetic, environmental, and lifestyle factors. The increased exposure to bisphenols, a chemical used in large quantities for the production of polycarbonate plastics, has raised concerns regarding health risks in humans, particularly their endocrine-disrupting effects on female reproductive health. To provide a basis for future research on environmental interference and reproductive health, we reviewed relevant studies on the exposure patterns and levels of bisphenols in environmental matrices and humans (including susceptible populations such as pregnant women and children). In addition, we focused on in vivo, in vitro, and epidemiological studies evaluating the effects of bisphenols on the female reproductive system (the uterus, ovaries, fallopian tubes, and vagina). The results indicate that bisphenols cause structural and functional damage to the female reproductive system by interfering with hormones; activating receptors; inducing oxidative stress, DNA damage, and carcinogenesis; and triggering epigenetic changes, with the damaging effects being intergenerational. Epidemiological studies support the association between bisphenols and diseases such as cancer of the female reproductive system, reproductive dysfunction, and miscarriage, which may negatively affect the establishment and maintenance of pregnancy. Altogether, this review provides a reference for assessing the adverse effects of bisphenols on female reproductive health.

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