Méthode de préconcentration par extraction en phase solide : principe et application aux industries environnementales et pétrolières

Chapuis, Florence; Pichon, Valérie; Hennion, M.

doi:10.2516/ogst:2005063

Cited by 4 publications

(2 citation statements)

References 42 publications

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“…Pretreatment of environmental samples is an essential step seeing the complexity of the matrix (indicating the constituents of the sample other than the analyte of interest) and the low concentrations of the compounds resided in the aquatic environment. The purpose of this step is to concentrate the analytes in question while trying to eliminate probable interferences (Chapuis et al 2005). The majority of the included studies used solid-phase extraction (SPE) for the sample preparation consisting of the extraction and the preconcentration of anticancer drugs (Table S3).…”

Section: Extraction and Determination Techniques Extractionmentioning

confidence: 99%

Occurrence of anticancer drugs in the aquatic environment: a systematic review

Nassour

Barton

Nabhani‐Gebara

et al. 2019

Environ Sci Pollut Res

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Water contamination with pharmaceutical products is a well-studied problem. Numerous studies have demonstrated the presence of anticancer drugs in different water resources that failed to be eliminated by conventional wastewater treatment plants. The purpose of this report was to conduct a systematic review of anticancer drugs in the aquatic environment. The methodology adopted was carried out in compliance with the PRISMA guidelines. From the 75 studies that met the specific requirements for inclusion, data extracted showed that the most common anticancer drugs studied are cyclophosphamide, tamoxifen, ifosfamide and methotrexate with concentrations measured ranging between 0.01 and 86,200 ng/L. There was significant variation in the methodologies employed due to lack of available guidelines to address sampling techniques, seasonal variability and analytical strategy. The most routinely used technique for quantitative determination was found to be solid-phase extraction followed by LC-MS analysis. The lowest reported recovery percentage was 11%, and the highest limit of detection was 1700 ng/L. This indicated the inadequacy of some methods to analyse anticancer drugs and the failure to obtain reliable results. The significant heterogeneity within methodologies made it difficult to compare results and draw conclusions, nevertheless, this study aids in the extrapolation of proposed recommendations to guide future studies and reviews.

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Section: Extraction and Determination Techniques Extractionmentioning

confidence: 99%

Occurrence of anticancer drugs in the aquatic environment: a systematic review

Nassour

Barton

Nabhani‐Gebara

et al. 2019

Environ Sci Pollut Res

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“…Il s'agit de groupements fonctionnels hydrophobes et notamment la silice greffée par des chaînes hydrocarbonées de type C18, C8. Ces supports créent des rétentions basées sur des interactions de type hydrophobes [1]. Les groupements fonctionnels disponibles permettent de répondre à tout type d'extraction (tableau I).…”

Section: Introductionunclassified

Extraction en phase solide (SPE) : théorie et applications

Humbert

2010

Ann Toxicol Anal

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Résumé -L'extraction en phase solide (SPE) est devenue depuis quelques années une technique de préparation d'échantillons de plus en plus utilisée en toxicologie analytique. Son principe de base est analogue à celui de la chromatographie de partage. Depuis son apparition de nombreuses phases stationnaires ont été développées par les industriels, permettant des extractions de plus en plus ciblées, ou bien adaptées pour l'extraction d'un grand nombre de substances de natures chimiques variées : pour une recherche large de xénobiotiques en milieu hospitalier pour des patients admis aux urgences ou en médecine légale dans les recherches des causes de la mort. De par la diversité des phases stationnaires elle permet l'extraction de composés polaires difficilement extractibles auparavant par les phases organiques. L'extraction se déroule généralement en quatre étapes : le conditionnement de la phase stationnaire, le chargement de l'échantillon, le(s) lavage(s) de la cartouche et enfin l'élution. La maîtrise de ce pré-analytique permet des facteurs de pré-concentration de(s) analyte(s) à rechercher ou à doser qui peut abaisser la limite de détection d'une méthode. Les larges gammes commercialisées par les industriels sont adaptées à des extractions ponctuelles de volumes très variés (de quelques dizaines de microlitres à plusieurs millilitres voire litres) mais aussi à l'extraction de grandes séries grâce à des plaques de 96 puits. C'est aussi une technique qui a l'avantage d'être automatisable. De très nombreuses mé-thodes analytiques ont été développées sur les matrices biologiques habituelles : le sérum, le plasma ou les urines mais également dans des matrices plus complexes comme les cheveux ou le méconium. Mots clés : Extraction, phase stationnaire, matrices biologiquesAbstract -Solid phase extraction (SPE) has become, in recent years, a technique for sample preparation increasingly used in analytical toxicology. Its basic principle is similar to that of partition chromatography. Since its appearance, many stationary phases have been developed by industry for more targeted extractions or adapted for the extraction of a large number of chemical substances of various kinds for a wide search for xenobiotics in hospital for patients admitted to the emergency ward, or forensic research into the causes of death. Because of the variety of stationary phases it allows the extraction of polar compounds from previously difficult to extract organic phases. The extraction is generally conducted in four steps: conditioning of the stationary phase, loading of the sample, washing(s) of the cartridge and finally, elution. Control of this pre-analytical stage allows factors of pre-concentration of the analyte(s) to search for or to be determined which can lower the limit of detection of a method. The wide ranges marketed by the industry are suitable for specific extraction of very varied volumes (a few tens of microliters up to several mL or liters) but also for extraction of large sets with plates of 96 wells. It is also a techniq...

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Molecular imprinting science and technology: a survey of the literature for the years 2004-2011

2014

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SummaryHerein we present a survey of the literature covering the development of molecular imprinting science and technology over the years 2004 to 2011. In total, 3779 references to the original papers, reviews, edited volumes and monographs from this period are included, along with recently identified uncited materials from prior to 2004 which were omitted in the first instalment of this series covering the years 1930 to 2003. 1 In the presentation of the assembled references, a section presenting reviews and monographs covering the area is followed by sections describing fundamental aspects of molecular imprinting including the development of novel polymer formats. Thereafter, literature describing efforts to apply these polymeric materials to a range of application areas is presented. Current trends and areas of rapid development are discussed.2

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Méthode de préconcentration par extraction en phase solide : principe et application aux industries environnementales et pétrolières

Cited by 4 publications

References 42 publications

Occurrence of anticancer drugs in the aquatic environment: a systematic review

Occurrence of anticancer drugs in the aquatic environment: a systematic review

Extraction en phase solide (SPE) : théorie et applications

Molecular imprinting science and technology: a survey of the literature for the years 2004-2011

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