Method for range calculation based on empirical models of proton in liquid water: Validation study using Monte-Carlo method and ICRU data.

Krim, M.; Harakat, N.; Khouaja, A.; Inchaouh, J.; Mesradi, M.R.; Chakir, H.; Kartouni, Abdelkrim; Marouane, A; Benjellοun, Mohammed; Boudhaim, S; Fiak, M.; Bouhssa, M. L.; Houssni, Z

doi:10.14299/ijser.2017.03.007

Cited by 8 publications

(10 citation statements)

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“…Results are shown in Table I below. 21,22) The results obtained are in good agreement with the ICRU Data as well as with the other platforms of the Monte Carlo method, which confirms the reliability of our code used in the simulation.…”

Section: Methodssupporting

confidence: 79%

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Monte Carlo simulation of the lateral spread for proton beams in voxelized water phantom using GEANT4 platform

Kaanouch

Krim

Ghazi

et al. 2023

Jpn. J. Appl. Phys.

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An evaluation of the lateral spread that the proton beams undergo during their interactions with a water phantom has been performed. We calculated and evaluated the dose distribution spatially deposed of protons acceleration up to energies between 70 and 215 MeV using a voxelized water phantom as a 3D detector. A 0.1 mm3 size precision voxel was used to detect and calculate the deposed energy and dose in any area of the water phantom using the GEANT4 platform based on the Monte-Carlo Method simulation. We find that, regardless of the initial proton energy, the lateral spread follows a parabolic pattern as a function of depth, and the ratio of the radius at the Bragg peak to the depth of the Bragg peak is around 2.8%. A good agreement has been found compared to other analytical models, simulation methods, and especially to experimental data.

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Section: Methodssupporting

confidence: 79%

“…We show in Fig. 5 the relationship that could govern the Bragg peak range R (cm) of a proton beam in liquid water: 21)…”

Section: Resultsmentioning

confidence: 99%

Monte Carlo simulation of the lateral spread for proton beams in voxelized water phantom using GEANT4 platform

Kaanouch

Krim

Ghazi

et al. 2023

Jpn. J. Appl. Phys.

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“…Figure 4 shows the range of protons in liquid water 6,[54][55][56][57][58][59][60][61] . Although the stopping power calculated by ATIMA was modulated by the restricted stopping power algorithm, the calculated range concurs with literature data.…”

Section: Resultsmentioning

confidence: 99%

Development and Validation of Proton Track Structure Model Applicable to Arbitrary Materials

Ogawa

Hirata

Matsuya

et al. 2021

Preprint

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A novel transport algorithm performing proton track-structure calculations in arbitrary materials was developed. Unlike conventional algorithms, which are based on the dielectric function of the target material, our algorithm uses a total stopping power formula and single-differential cross sections of secondary electron production. The former was used to simulate energy dissipation of incident protons and the latter was used to consider secondary electron production. In this algorithm, the incident proton was transmitted freely in matter until the proton produced a secondary electron. The corresponding ionising energy loss was calculated as the sum of the ionisation energy and the kinetic energy of the secondary electron whereas the non-ionising energy loss was obtained by subtracting the ionising energy loss from the total stopping power. The most remarkable attribute of this model is its applicability to arbitrary materials, i.e. the model utilises the total stopping power and the single-differential cross sections for secondary electron production rather than the material-specific dielectric functions. Benchmarking of the stopping range, radial dose distribution, secondary electron energy spectra in liquid water, and lineal energy in tissue-equivalent gas, against the experimental data taken from literature agreed well. This indicated the accuracy of the present model even for materials other than liquid water. Regarding microscopic energy deposition, this model will be a robust tool for analysing the irradiation effects of cells, semiconductors and detectors.

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“…Fitted parameters for new model of excitation and charge-transfer cross section. In last work, [4][5][6] we have investigated different inelastic interactions of protons and neutral hydrogen atoms beams in liquid water. These interactions include not only excitation and ionization processes of protons, but also charge-transfer and ionization, excitation, and electron loss of moving neutral hydrogen atoms.…”

Section: Proposed Analytical Model For Proton Excitation and Charge-t...mentioning

confidence: 99%

“…Secondly, the absence of model calculate excitation and chargetransfer cross sections leads us to adopt the Laverne and Pimblott 3) work, we postulate that the ratios between the cross section of ionization and excitation, and between the ionization and charge-transfer in adenine and liquid water are the same. These ratios in liquid water were calculated using our previous work, [4][5][6] and analytical fitting expression found via the adjustment, is used to summarize the relationship of these ratios and energy incident. Starting this way allows one to calculate rather easily the excitation and charge-transfer cross sections in adenine by solving proportions.…”

Section: Introductionmentioning

confidence: 99%

Cross sections, stopping power and Bragg peak range calculation of proton collisions with the DNA base adenine

Krim

Inchaouh

Harakat

et al. 2019

Jpn. J. Appl. Phys.

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Passage of ionizing radiation into the biological medium plays an important role in a variety of chemical modifications, directly or indirectly of the four DNA bases. However, up to now proton collisions on DNA bases remain experimentally approached and a theoretical model for total cross section, stopping cross section and Bragg peak calculation are poorly characterized. In this current work, we restricted our study on the interaction of energetic ion proton beams with DNA base adenine (C5H5N5). The total cross section produced by high energy impact of protons are here analytically investigated via a novel model combining two methods-the Rudd semi-empirical formulas to calculate the ionization and the analytic method based on the similitude between the electron energy loss in adenine and liquid water to calculate the excitation and charge-transfer-these cross sections used to describe the total stopping cross section of adenine molecule by protons including the nuclear stopping powers. We give in this work an estimation of the Bragg peak profile and position with impact energies ranging from 1 to 20 MeV/amu. The results are compared to the available experimental, theoretical and Monte-Carlo results, and reasonable agreements are generally observed especially for the ionization. The proposed method is useful as an alternative to traditional approaches, and is useful for studies of various radiation effects in other biological material.

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Method for range calculation based on empirical models of proton in liquid water: Validation study using Monte-Carlo method and ICRU data.

Cited by 8 publications

References 0 publications

Monte Carlo simulation of the lateral spread for proton beams in voxelized water phantom using GEANT4 platform

Monte Carlo simulation of the lateral spread for proton beams in voxelized water phantom using GEANT4 platform

Development and Validation of Proton Track Structure Model Applicable to Arbitrary Materials

Cross sections, stopping power and Bragg peak range calculation of proton collisions with the DNA base adenine

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