Methicillin-Resistant Staphylococcus aureus (MRSA) in Food- Producing and Companion Animals and Food Products

Chon, Jung‐Whan; Sung, Kidon; Khan, Saeed

doi:10.5772/66645

Cited by 15 publications

(12 citation statements)

References 281 publications

(325 reference statements)

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“…However, infections by LA-MRSA were also found in people without livestock exposure [ 17 , 18 ]. ST398 and several others (ST9, ST97, ST5) have been isolated from pork, chicken, beef, and milk in many countries [ 19 ]. These finding demonstrate that handling and/or consumption of food-producing animals contaminated by MRSA is a potential zoonotic transmission source for humans [ 20 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Resistance and Molecular Characterization of Methicillin-Resistant Staphylococcus aureus Isolated from Slaughtered Pigs and Pork in the Central Region of Thailand

et al. 2021

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Methicillin-resistant Staphylococcus aureus (MRSA) have been a major public health concern in humans. Among MRSA, livestock-associated (LA)-MRSA strains have always been associated with exposure to livestock or their products and have emerged in different countries globally. Although studies have identified LA-MRSA from healthy pigs and pork in Thailand, prevalence in slaughtered pigs is still unknown. In addition, there are few reports on the epidemiology and molecular characteristics of LA-MRSA in Thailand. Hence, this is the first report investigating the epidemiology and molecular characteristics of MRSA in individual slaughtered pigs and pork in Thailand. A total of 204 nasal swab and 116 retailed pork samples were collected from three slaughterhouses and four fresh markets, respectively. Individual samples were used for screening for MRSA and obtained isolates were examined for drug- resistance profiling for 12 antimicrobial agents of 10 drug classes. In addition, SCCmec typing and multi-locus sequence typing were conducted to obtain genotype profiles. MRSA were isolated from 11 and 52 nasal swab and pork samples, respectively. The prevalence was significantly higher in the pork than in the nasal swab samples (p-value < 0.05). A high prevalence of ST9-SCCmecIX and ST398-SCCmecV with high-level antimicrobial resistance from markets and slaughterhouses indicated the spreading of MRSA with these genotypes in the Thai swine processing chains and suggested the need for further investigation to determine a control.

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Section: Introductionmentioning

confidence: 99%

Antimicrobial Resistance and Molecular Characterization of Methicillin-Resistant Staphylococcus aureus Isolated from Slaughtered Pigs and Pork in the Central Region of Thailand

et al. 2021

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“…In addition to these, there has been a third MRSA group, known as LA-MRSA. Today, LA-MRSA has come to existed and infected to farm animals, wild animals and pets [29]. In addition of these, MRSA has been found variety of animal origin foods (beef, poultry and pig meats and milk like that).…”

Section: Mrsa Types According To Originmentioning

confidence: 99%

“…In the early 1970s, in Belgium, the first MRSA report in farm animals (dairy cows' milk of with mastitis) was published, and the clustered CC398 group was identified [29]. In Korea, MRSA has been found in cows or cows' milk samples [63].…”

Section: Mrsa In Foodsmentioning

confidence: 99%

A General Outlook on Methicillin Resistant Staphylococcus aureus

Sırıken

Inat

Çiftci

2018

JAMB

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Methicillin resistant Staphylococcus aureus (MRSA) is a kind of bacteria which is resistant against methicillin and other kind of many antibiotics. S. aureus and MRSA can lead to serious problem in human as well as animals. The problem can be simple or sometimes serious such as skin infections, sepsis, pneumonia and bloodstream infections. Firstly, MRSA was largely related to hospital-acquired (HA) infection. However, it is well understood that there is other source of MRSA. Nowadays, MRSA has been divided three group; (1) Hospital-Associated MRSA (HA-MRSA), (2) Community-Acquired MRSA (CA-MRSA) and (3) Livestock-Associated MRSA (LA-MRSA). In addition to the three groups, MRSA has been found variety of animal origin foods (beef, poultry and pig meats and milk like that). Therefore, food of animal origin can contaminate with MRSA bacteria,

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“…5 The presence of methicillin-resistant S. aureus strains (MRSA) in food-producing animals and its detection in retail meat samples raises the concern about the potential food-borne transmission of MRSA. 6 Before the 1990s, the majority of MRSA cases were hospital-associated (HA-MRSA); however, the community-associated MRSA (CA-MRSA) then found to cause infections outside the healthcare environment. The third major emergent type of MRSA has been reported in livestock animals [livestock-associated MRSA (LA-MRSA)].…”

Section: Introductionmentioning

confidence: 99%

<p>Pathways of Methicillin-Resistant <em>Staphylococcus aureus</em> in Animal Model: New Insights Regarding Public Health</p>

Hamza

Abd‐Elsalam

Nader

et al. 2020

IDR

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Background: Staphylococcus aureus is considered one of the major threats regarding food safety worldwide. Methicillin-resistant S. aureus (MRSA) strains in livestock, companion animals, and wild animals continue to be a potential risk to people working with them. Aim: The current research aims to investigate the potential pathways of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) strains in the body after oral infection using the experimental mouse model. Methods: Seven groups of SPF male mice were purchased and housed. On day 1, six groups of mice were infected orally by the sterile gastric probe using 100 μL/mice of LA-MRSA bacterial suspension (1 × 10 8 colony-forming units (CFU)/mL). The remaining group was kept as negative controls. Over 15 days, these animals have been monitored. Fresh fecal samples were screened for LA-MRSA at day 0, day 7 and day 14 following oral administration of MRSA strains. All animals were sacrificed at day 15, and internal organs (liver, lung, kidney, and intestine) were harvested aseptically and divided into two sections. The first part was histopathologically investigated, while the other half has been tested for LA-MRSA re-isolation. Result: The oral challenge of mice by MRSA strains showed that MRSA was re-isolated from feces and intestines of all inoculated mice groups and from internal organs (liver, lung, kidney and intestine) of most mice. Results were confirmed by the detection of the bacteria in gram-stained tissue sections and changes in H&E-stained histopathological tissue sections from these organs. Conclusion: Data from the present study indicate the possible colonization of livestockassociated methicillin-resistant Staphylococcus aureus (LA-MRSA) in internal organs following oral infection and thus posing a risk for food-borne infection of MRSA. Infected animals could pass LA-MRSA through feces again, resulting in increased dispersion and environmental contamination.

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Methicillin-Resistant Staphylococcus aureus (MRSA) in Food- Producing and Companion Animals and Food Products

Cited by 15 publications

References 281 publications

Antimicrobial Resistance and Molecular Characterization of Methicillin-Resistant Staphylococcus aureus Isolated from Slaughtered Pigs and Pork in the Central Region of Thailand

Antimicrobial Resistance and Molecular Characterization of Methicillin-Resistant Staphylococcus aureus Isolated from Slaughtered Pigs and Pork in the Central Region of Thailand

A General Outlook on Methicillin Resistant Staphylococcus aureus

<p>Pathways of Methicillin-Resistant <em>Staphylococcus aureus</em> in Animal Model: New Insights Regarding Public Health</p>

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