Methicillin-resistant Staphylococcus aureus and Staphylococcus pseudintermedius in veterinary medicine

Abstract

Staphylococci are important opportunistic pathogens in most animal species. Among the most relevant species are the coagulase positive species Staphylococcus aureus and Staphylococcus pseudintermedius. Methicillin resistance has emerged as an important problem in both of these organisms, with significant concerns about animal and public health. The relative importance of these staphylococci on different animal species varies, as do the concerns about zoonotic transmission, yet it is clear that both present a challenge to veterinary medicine.

Prevalence and in vitro susceptibility of methicillin-resistant Staphylococcus pseudintermedius (MRSP) from skin and nostrils of dogs with superficial pyoderma

“…However, in the last three decades the prevalence of strains resistant to those drugs has increased (Weese & Van Duijkeren 2010, Beck et al 2012) This is a notorious problem in veterinary dermatology, since beta-lactamic antibiotics are the first choice option in the treatment of bacterial pyoderma (Miller et al 2013). Such resistant strains are called methicillin-resistant Staphylococcus pseudintermedius (MRSP) (Weese & Van Duijkeren 2010).…”

“…However, in the last three decades the prevalence of strains resistant to those drugs has increased (Weese & Van Duijkeren 2010, Beck et al 2012) This is a notorious problem in veterinary dermatology, since beta-lactamic antibiotics are the first choice option in the treatment of bacterial pyoderma (Miller et al 2013). Such resistant strains are called methicillin-resistant Staphylococcus pseudintermedius (MRSP) (Weese & Van Duijkeren 2010). The MRSP strains carry the mecA gene, which encodes an altered penicillin-binding protein known as PBP2a, which reduces the bacterial affinity to all beta-lactamic antibiotics (Weese & Van Duijkeren 2010, Wang et al 2012.…”

“…Such resistant strains are called methicillin-resistant Staphylococcus pseudintermedius (MRSP) (Weese & Van Duijkeren 2010). The MRSP strains carry the mecA gene, which encodes an altered penicillin-binding protein known as PBP2a, which reduces the bacterial affinity to all beta-lactamic antibiotics (Weese & Van Duijkeren 2010, Wang et al 2012.…”

Evolution of Multidrug-ResistantStaphylococcus aureusInfections in Horses and Colonized Personnel in an Equine Clinic Between 2005 and 2010

“…17,31,35,38,42 Specific MRSA belonging to clonal complexes CC1, CC5, CC8, CC22, CC59, CC88, CC398, and mainly to spa type t002, t008, t009, t011, t020, t022, t032, t034, t036, t064, t127, t166, t186, t216, t451, t588, t1197, t1451, and t2123 have been identified as a cause of nosocomial infections in numerous equine clinics. 9,27,[37][38][39]43 S. aureus can colonize the skin and mucosa, especially nasal mucosa, of healthy horses and humans, which then acts as a reservoir for MRSA and contributes to its spread into the community and hospitals.…”

Comparison of Dog and Rabbit Plasmas in the Tube Coagulase Test for Staphylococcus Aureus

“…"content-markup(./author-grp [1]/aff|./author-grp [1]/dept-list)> Staphylococcus aureus is one of the most common causes of infections in people worldwide, and it is increasingly recognized in companion animals, including dogs. 4,9 Recent reports of the increasing prevalence of methicillinresistant S. aureus (MRSA) in people and animals have raised awareness in the veterinary community about this potential pathogen. 6,7 Staphylococcus aureus is identified using a number of standard biochemical tests, including the tube coagulase test, typically using rabbit plasma.…”