“…Studies have been conducted in at least three cities and are possibly ongoing in other cities to determine the feasibility and effectiveness of medical maintenance treatment for long-term methadone-maintained patients who have had a good record of treatment performance to be treated in a general clinic or "office based" practice. In the New York City studies, under the leadership of Novick, patients who have had at least 5 years of methadone maintenance treatment in a standard clinic, with excellent performance, that is, with cessation of all illicit opiate use and no ongoing polydrug or alcohol abuse, all positive indicators for rehabilitation, met the inclusion criteria (NOVICK et al 1988a(NOVICK et al ,b, 1990(NOVICK et al , 1994NOVICK and JOSEPH 1991). In this medical maintenance study, patients are seen as infrequently as once every 4 weeks or not more often than once a week, in a medical office (not a drug abuse treatment program) at which time they provide a urine speciment for drug monitoring, take one daily dose of methadone under observation, and undergo a conventional medical, and also intense drug use history, physical examination, and when appropriate, other laboratory testing.…”