Abstract:Background: The effect of metformin on the risk of atrial fibrillation (AF) requires confirmation. This study compared the incidence of hospitalization for AF in ever and never users of metformin. Methods: Patients with newly diagnosed type 2 diabetes mellitus during 1999-2005 were enrolled from Taiwan’s National Health Insurance database. Analyses were conducted in both an unmatched cohort of 173398 ever users and 21666 never users and in a propensity score-matched cohort of 21647 pairs of ever and never user… Show more
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