Metformin Is Associated With Improved Inflammatory Bowel Disease Outcomes in Patients With Type 2 Diabetes Mellitus: A Propensity-Matched Cohort Study
Jessica C Petrov,
Aakash A Desai,
Gursimran S Kochhar
et al.
Abstract:Background
Metformin exerts anti-inflammatory properties through a positive effect on oxidative stress, gut barrier integrity, and the gut microbiota. Our aim was to evaluate the influence of metformin on inflammatory bowel disease (IBD) outcomes in patients with type 2 diabetes mellitus (T2DM).
Methods
We conducted a retrospective cohort study using the TriNetX database in patients with IBD and T2DM who initiated metformin v… Show more
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