Abstract:Metatranscriptomics has not yet been applied to the study of the endodontic microbiome. Therefore, this study investigated the microbial composition and patterns of gene expression in teeth with asymptomatic apical periodontitis. We performed next-generation, microbiome- wide RNA-sequencing in eight root canal samples, including five primary and three secondary endodontic infections. Proteobacteria, Bacteroidetes, Firmicutes and Actinobacteria represented the dominant phyla, whereas Fusobacteria, Spirochaetes … Show more
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