Metasurfaces for Quantitative Biosciences of Molecules, Cells, and Tissues: Sensing and Diagnostics

Barulin, Aleksandr; Nguyen, Dang Du; Kim, Yangkyu; Ko, Chihe; Kim, Inki

doi:10.1021/acsphotonics.3c01576

Cited by 4 publications

(1 citation statement)

References 103 publications

(227 reference statements)

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“…A figure schematically representing a MS-based selective metasensor of molecules is shown in Figure 27. Potential applications include low-cost sensors combined with cellphones transmitting patient data directly to clinical centers [411] (wearable self-testing systems), advanced lab-on-a-chip systems using metasurface-based biosensors [412], MS platforms for the sensing of biomarkers of different kinds of malignant tumors, viral diseases and neurodegenerative issues [413] and generally precision medicine.…”

Section: Perspectives (Possible Research Directions To Overcome Chall...mentioning

confidence: 99%

Synergy between AI and Optical Metasurfaces: A Critical Overview of Recent Advances

Jakšić

2024

Photonics

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The interplay between two paradigms, artificial intelligence (AI) and optical metasurfaces, nowadays appears obvious and unavoidable. AI is permeating literally all facets of human activity, from science and arts to everyday life. On the other hand, optical metasurfaces offer diverse and sophisticated multifunctionalities, many of which appeared impossible only a short time ago. The use of AI for optimization is a general approach that has become ubiquitous. However, here we are witnessing a two-way process—AI is improving metasurfaces but some metasurfaces are also improving AI. AI helps design, analyze and utilize metasurfaces, while metasurfaces ensure the creation of all-optical AI chips. This ensures positive feedback where each of the two enhances the other one: this may well be a revolution in the making. A vast number of publications already cover either the first or the second direction; only a modest number includes both. This is an attempt to make a reader-friendly critical overview of this emerging synergy. It first succinctly reviews the research trends, stressing the most recent findings. Then, it considers possible future developments and challenges. The author hopes that this broad interdisciplinary overview will be useful both to dedicated experts and a general scholarly audience.

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Section: Perspectives (Possible Research Directions To Overcome Chall...mentioning

confidence: 99%

Synergy between AI and Optical Metasurfaces: A Critical Overview of Recent Advances

Jakšić

2024

Photonics

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Designer Metasurfaces via Nanocube Assembly at the Air–Water Interface

Fajri,

Kossowski,

Bouanane

et al. 2024

ACS Nano

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The advent of metasurfaces has revolutionized the design of optical instruments, and recent advancements in fabrication techniques are further accelerating their practical applications. However, conventional top-down fabrication of intricate nanostructures proves to be expensive and timeconsuming, posing challenges for large-scale production. Here, we propose a cost-effective bottom-up approach to create nanostructure arrays with arbitrarily complex meta-atoms displaying single nanoparticle lateral resolution over submillimeter areas, minimizing the need for advanced and highcost nanofabrication equipment. By utilizing air/water interface assembly, we transfer nanoparticles onto templated polydimethylsiloxane (PDMS) irrespective of nanopattern density, shape, or size. We demonstrate the robust assembly of nanocubes into meta-atoms with diverse configurations generally unachievable by conventional methods, including U, L, cross, S, T, gammadion, split-ring resonators, and Pancharatnam−Berry metasurfaces with designer optical functionalities. We also show nanocube epitaxy at near ambient temperature to transform the meta-atoms into complex continuous nanostructures that can be swiftly transferred from PDMS to various substrates via contact printing. Our approach potentially offers a large-scale manufacturing alternative to top-down fabrication for metal nanostructuring, unlocking possibilities in the realm of nanophotonics.

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Modern age of pathological sciences: fluorescence microscopy for proficient treatment

Satti,

Javed,

Zubair

et al. 2024

Clinical Biophotonics III

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In light microscopy, achieving uniform lighting throughout the field of view is essential to obtain clear images. However, thicker samples commonly suffer from image blur due to out-of-focus illumination, notably raised in fluorescence microscopy because dye molecules are activated across all planes, including those out of focus. Confocal-type fluorescence microscopy efficiently addresses this obstacle by reducing out-of-focus light, thereby permitting high-quality imaging in thick tissues. By focusing the light and detector on a diffraction-limited point and monitoring the material point by point, confocal microscopes may obtain full pictures with optical sectioning abilities for 3D reconstruction. With numerous varieties offering distinct advantages and limits, confocal microscopes serve as important tools for accurate imaging and analysis across different sectors. This article gives a concise review of confocal fluorescence microscopy.

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Metasurfaces for Quantitative Biosciences of Molecules, Cells, and Tissues: Sensing and Diagnostics

Cited by 4 publications

References 103 publications

Synergy between AI and Optical Metasurfaces: A Critical Overview of Recent Advances

Synergy between AI and Optical Metasurfaces: A Critical Overview of Recent Advances

Designer Metasurfaces via Nanocube Assembly at the Air–Water Interface

Modern age of pathological sciences: fluorescence microscopy for proficient treatment

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