Metastatic Tumors to the Stomach: Analysis of 54 Patients Diagnosed at Endoscopy and 347 Autopsy Cases

Abstract

Since metastatic lesions to the stomach are rare, the above characteristics of the lesions should be borne in mind, and biopsies should be taken for precise diagnosis during endoscopic examinations.

Metastatic melanoma of the stomach and the duodenum

“…The average rate of GIT metastases detected clinically in malignant melanoma patients antemortem is only 2.3%, but varies from 0.8% to 8.9% in different series (3,4). The overall incidence of GIT metastases detected post mortem in autopsies of patients who died from disseminated malignant melanoma is in excess of 60% of the cases (3,5). The most common Figure 3.…”

“…The small bowel is the most common intestinal site for metastases (3). Information on gastric and duodenal metastases, however, is merely limited to single case reports.…”

A Case of Metastatic Squamous Cell Carcinomas from the Endocervix to the Stomach without Local Recurrence

“…5,10,11 On the other hand, the most prevalent primary sites of metastasis to the stomach are the lung, breast, skin (melanoma), and esophagus. Lung and breast neoplasia were the most common primary sites of gastric metastases in several series, 9,[12][13][14] and these findings reflect the high incidence of these tumors among the general population. Corroborating the data from other authors, the clinical symptom most frequently requiring an EGD in this series, was upper gastrointestinal bleeding.…”

“…Corroborating the data from other authors, the clinical symptom most frequently requiring an EGD in this series, was upper gastrointestinal bleeding. [12][13][14] Within the subgroup of patients with cancer of the esophagus, the symptoms justifying EGD were dysphagia and chest pain. Unfortunately, the diagnosis of metastasis in the symptomatic phase signifies a late diagnosis, at a stage which renders any treatment procedure ineffective.…”

“…The macroscopic features observed by EGD vary considerably and are, therefore, not specific of metastatic disease. Oda et al 12 in a large series, list eight different endoscopic manifestations. The case we have described showed a predominance of ulcerofungating lesions, resembling advanced gastric carcinoma.…”